Antitumor Activity of Polysaccharides: An Overview

被引：120

作者：

Chen, Ling ^{[1
]}

Huang, Gangliang ^{[1
]}

机构：

[1] Chongqing Normal Univ, Coll Chem, Act Carbohydrate Res Ctr, Chongqing 401331, Peoples R China

来源：

CURRENT DRUG TARGETS | 2018年 / 19卷 / 01期

关键词：

Polysaccharides; antitumor; biological activities; mechanisms; discuss; summarize; GANODERMA-LUCIDUM POLYSACCHARIDES; STRUCTURAL-CHARACTERIZATION; HEPATOCELLULAR-CARCINOMA; DENDRITIC CELLS; IMMUNOMODULATORY ACTIVITY; PROTEIN COMPLEX; MCF-7; CELLS; IN-VITRO; CANCER; INHIBITION;

D O I：

10.2174/1389450118666170704143018

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Background: Polysaccharides are widely found in animals, plants and micro-organisms, and are closely related to various physiological functions. It is one of the four basic substances that constitute life activities. Polysaccharide has antitumor, antivirus, antioxidant, immune regulation and other biological activities. Objective: Because the polysaccharide has significant antitumor effect and small side-effects, it has become the focus of the current antitumor drug research. Results: Herein, the polysaccharide species with antitumor effect were summarized in recent years, and the antitumor activity mechanisms of polysaccharides were analyzed and discussed. Conclusion: Many polysaccharides have good antitumor activity, and they have broad application prospects.

引用

页码：89 / 96

页数：8

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