The MATRICS Consensus Cognitive Battery (MCCB): Co-norming and standardization in Spain

被引:64
作者
Rodriguez-Jimenez, R. [1 ,2 ]
Bagney, A. [1 ,2 ]
Garcia-Navarro, C. [1 ,2 ]
Aparicio, A. I. [3 ]
Lopez-Anton, R. [2 ]
Moreno-Ortega, M. [1 ]
Jimenez-Arriero, M. A. [1 ,2 ]
Santos, J. L. [3 ]
Lobo, A. [2 ,4 ,5 ]
Kern, R. S. [6 ,7 ]
Green, M. F. [6 ,7 ]
Nuechterlein, K. H. [6 ,8 ]
Palomo, T. [1 ,2 ]
机构
[1] Hosp 12 Octubre, Dept Psychiat, Inst Invest, E-28041 Madrid, Spain
[2] Ctr Invest Biomed Red Salud Mental CIBERSAM, Madrid, Spain
[3] Hosp Virgen La Luz, Dept Psychiat, Cuenca, Spain
[4] Hosp Clin Univ, Dept Psychiat, Zaragoza, Spain
[5] Univ Zaragoza, Zaragoza, Spain
[6] Univ Calif Los Angeles, David Geffen Sch Med, Semel Inst Neurosci & Human Behav, Los Angeles, CA 90095 USA
[7] VA Greater Los Angeles Healthcare Syst, Los Angeles, CA USA
[8] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA
关键词
Schizophrenia; Cognition; MATRICS; MCCB; MINI-MENTAL STATE; SOCIAL COGNITION; NEUROCOGNITIVE DEFICITS; INDIVIDUAL-DIFFERENCES; MEMORY PERFORMANCE; SEX-DIFFERENCES; LIFE-SPAN; SCHIZOPHRENIA; NEUROSCIENCE; EMOTION;
D O I
10.1016/j.schres.2011.11.026
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The MATRICS Consensus Cognitive Battery (MCCB), developed by the National Institute of Mental Health (NIMH) Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative, has been recommended as the standard battery for clinical trials of cognition-enhancing interventions for schizophrenia. Normative data for the MCCB has been previously obtained in the U.S. Extrapolation of these normative data to different countries may be problematic due to the translation of the different tests, as well as potential cultural influences. We present the process of obtaining normative data for the MCCB in Spain with administration of the battery to a general community standardization sample. In addition, we examine the influence of age, gender, and educational level on test performance. The MCCB was administered to a total sample of 210 healthy volunteers, at three Spanish sites. For each site, recruitment of the sample was stratified according to age, gender, and educational level. Our findings indicate significant age, gender, and education effects on the normative data for the MCCB in Spain, which are comparable to those effects described for the original standardized English version in the U.S. The fact that the normative data are comparable, and that the variables age, gender, and education have a similar influence on performance, supports the robustness of the MCCB for use in different countries. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:279 / 284
页数:6
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