Use of cardiac MR imaging to evaluate the presence of myocarditis in autoimmune myositis: three cases

被引:9
作者
Toong, Catherine [1 ,2 ]
Puranik, Rajesh [1 ,2 ]
Adelstein, Stephen [1 ,2 ]
机构
[1] Royal Prince Alfred Hosp, Camperdown, NSW 2050, Australia
[2] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia
关键词
Autoimmune myositis; Inflammatory myopathy; Myocarditis; Cardiac magnetic resonance imaging; HUMAN SKELETAL-MUSCLE; AUTOPSIED PATIENTS; POLYMYOSITIS; DERMATOMYOSITIS; TROPONIN; HEART;
D O I
10.1007/s00296-009-1324-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac involvement in patients with idiopathic inflammatory myopathies (autoimmune myositis) is important to detect because it confers an increased risk of mortality. However, detection of myocardial involvement is hampered by a lack of sensitivity of traditional non-invasive methods, and the finding of elevated cardiac troponin T levels that may be due to regenerating skeletal muscle, rather than myocardial damage. Here, we describe three cases of inflammatory myositis with elevated troponin T levels, and non-specific echocardiographic and ECG findings. Cardiac MR imaging was useful in the evaluation for the presence of myocarditis or alternative cardiac pathology.
引用
收藏
页码:779 / 782
页数:4
相关论文
共 13 条
[1]   Nitric oxide is a physiological substrate for mammalian peroxidases [J].
Abu-Soud, HM ;
Hazen, SL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (48) :37524-37532
[2]  
Bodor GS, 1997, CLIN CHEM, V43, P476
[3]   Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features -: A longitudinal study of 162 cases [J].
Dankó, K ;
Ponyi, A ;
Constantin, T ;
Borgulya, G ;
Szegedi, G .
MEDICINE, 2004, 83 (01) :35-42
[4]   CARDIAC INVOLVEMENT IN POLYMYOSITIS - CLINICOPATHOLOGIC STUDY OF 20 AUTOPSIED PATIENTS [J].
DENBOW, CE ;
LIE, JT ;
TANCREDI, RG ;
BUNCH, TW .
ARTHRITIS AND RHEUMATISM, 1979, 22 (10) :1088-1092
[5]   Cardiac troponin and β-type myosin heavy chain concentrations in patients with polymyositis or dermatomyositis [J].
Erlacher, P ;
Lercher, A ;
Falkensammer, J ;
Nassonov, EL ;
Samsonov, MI ;
Shtutman, VZ ;
Puschendorf, B ;
Mair, J .
CLINICA CHIMICA ACTA, 2001, 306 (1-2) :27-33
[6]   CARDIAC MANIFESTATIONS IN POLYMYOSITIS [J].
GOTTDIENER, JS ;
SHERBER, HS ;
HAWLEY, RJ ;
ENGEL, WK .
AMERICAN JOURNAL OF CARDIOLOGY, 1978, 41 (07) :1141-1149
[7]   THE HEART AND CARDIAC CONDUCTION SYSTEM IN POLYMYOSITIS-DERMATOMYOSITIS - A CLINICOPATHOLOGIC STUDY OF 16 AUTOPSIED PATIENTS [J].
HAUPT, HM ;
HUTCHINS, GM .
AMERICAN JOURNAL OF CARDIOLOGY, 1982, 50 (05) :998-1006
[8]   The heart in dermatomyositis and polymyositis [J].
Lundberg, I. E. .
RHEUMATOLOGY, 2006, 45 :18-21
[9]   Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance [J].
McCrohon, A ;
Moon, JCC ;
Prasad, SK ;
McKenna, WJ ;
Lorenz, CH ;
Coats, AJS ;
Pennell, DJ .
CIRCULATION, 2003, 108 (01) :54-59
[10]  
Ohata S, 2002, J RHEUMATOL, V29, P861