Acute pathological laughter

被引:16
作者
Okuda, DT [1 ]
Chyung, ASC [1 ]
Chin, CT [1 ]
Waubant, E [1 ]
机构
[1] Univ San Francisco, Div Neurol, Multiple Sclerosis Ctr, San Francisco, CA 94117 USA
关键词
pseudobulbar affect; inappropriate laughter; multiple sclerosis; pathological laughter;
D O I
10.1002/mds.20607
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Pseudobulbar affect is a condition characterized by uncontrollable episodes of inappropriate laughing or crying that are disproportionate and discordant to the situation at hand. We report on a 16-year-old woman presenting with acute pathological laughter in the context of CNS demyelinating disease. Brain MRI scans fortuitously obtained before and after the onset of this symptom demonstrated acute gadolinium-enhancing lesions in the cerebral peduncles. The etiology of this condition remains theoretical; however, the results here provide further insights into the pathways of emotional control. (c) 2005 Movement Disorder Society.
引用
收藏
页码:1389 / 1390
页数:2
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