Assessment of artemisinin and antioxidant activities of three wild Artemisia species of Algeria

被引：11

作者：

Ahmed-Laloui, Hamza ^{[1
]}

Zaak, Hadjer ^{[2
]}

Rahmani, Abderrahman ^{[1
]}

Kashi, Imad ^{[3
]}

Chemat, Smain ^{[4
]}

Miara, Mohamed Djamel ^{[6
]}

Cherb, Nora ^{[5
]}

Derdour, Mouna ^{[1
]}

机构：

[1] Biotechnol Res Ctr CRBt, Biotechnol & Agr Div, Anim Biotechnol Lab, Ali Mendjeli, Constantine, Algeria

[2] Biotechnol Res Ctr CRBt, Food Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[3] Biotechnol Res Ctr CRBt, Ind Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[4] Ctr Rech Sci & Tech Anal Physicochim CRAPC, Extract & Separat Tech Team, Algiers, Algeria

[5] Biotechnol Res Ctr CRBt, Environm Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[6] Ibn Khaldoun Univ, Fac Nat & Life Sci, Dept Nat & Life Sci, Tiaret, Algeria

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 24期

关键词：

Artemisia; artemisinin; biological activities; crystallization; HPLC analysis; CHEMICAL-COMPOSITION; ANNUA L; ASSISTED EXTRACTION; ESSENTIAL OIL; ANTIBACTERIAL; PURIFICATION; ANTIFUNGAL; ULTRASOUND;

D O I：

10.1080/14786419.2022.2025803

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Artemisinin, a natural product, has received considerable attention in the last few years as a potent antimalarial drug. This study reports the presence of Artemisinin in three Algerian wild Artemisia species assessed by HPLC method: A. herba-alba (AH), A. campestris subsp. glutinosa (AC), and A. judaica subsp sahariensis (AJ). The HPLC analysis of the hexane extracts, showed a difference in artemisinin content in studied species with a yield of 0.64%, 0.34% and 0.04% for AC, AH and AJ, respectively. Moreover, the level of artemisinin obtained in A. campestris was better than those found in A. sieberi and A. annua. This rate has been reported for the first time. Furthermore, the antiradical activities of methanolic extracts of plants were also tested. There was a remarkable antioxidant capacity found in all Artemisia methanolic extracts analysed.

引用

页码：6344 / 6352

页数：9

共 46 条

[11] Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases [J].

Cheong, Dorothy H. J. ;

Tan, Daniel W. S. ;

Wong, Fred W. S. ;

Thai Tran .

PHARMACOLOGICAL RESEARCH, 2020, 158

[12] Artemisia campestris L.: Ethnomedicinal, phytochemical and pharmacological review [J].

Dib, Ikram ;

Angenot, Luc ;

Mihamou, Atika ;

Ziyyat, Abderrahim ;

Titsb, Monique .

JOURNAL OF HERBAL MEDICINE, 2017, 7 :1-10

[13] Antioxidant activity of some algerian medicinal plants extracts containing phenolic compounds [J].

Djeridane, A ;

Yousfi, M ;

Nadjemi, B ;

Boutassouna, D ;

Stocker, P ;

Vidal, N .

FOOD CHEMISTRY, 2006, 97 (04) :654-660

[14] From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy [J].

Efferth, Thomas .

SEMINARS IN CANCER BIOLOGY, 2017, 46 :65-83

[15] Antioxidant activity and volatile components of Egyptian Artemisia judaica L. [J].

El-Massry, KF ;

El-Ghorab, AH ;

Farouk, A .

FOOD CHEMISTRY, 2002, 79 (03) :331-336

[16] Analysis of underivatized artemisinin and related sesquiterpene lactones by high-performance liquid chromatography with ultraviolet detection [J].

Ferreira, Jorge F. S. ;

Gonzalez, Javier M. .

PHYTOCHEMICAL ANALYSIS, 2009, 20 (02) :91-97

[17] Microwave-assisted extraction of artemisinin from Artemisia annua L [J].

Hao, JY ;

Han, W ;

Huang, SD ;

Xue, BY ;

Deng, X .

SEPARATION AND PURIFICATION TECHNOLOGY, 2002, 28 (03) :191-196

[18] Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.-Part IV: Crystallization [J].

Huter, Maximilian Johannes ;

Schmidt, Axel ;

Mestmaecker, Fabian ;

Sixt, Maximilian ;

Strube, Jochen .

PROCESSES, 2018, 6 (10)

[19] Artemisinin evaluation in Romanian Artemisia annua wild plants using a new HPLC/MS method [J].

Ivanescu, B. ;

Vlase, L. ;

Corciova, A. ;

Lazar, M. I. .

NATURAL PRODUCT RESEARCH, 2011, 25 (07) :716-722

[20] Antioxidant activity of plant extracts containing phenolic compounds [J].

Kähkönen, MP ;

Hopia, AI ;

Vuorela, HJ ;

Rauha, JP ;

Pihlaja, K ;

Kujala, TS ;

Heinonen, M .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (10) :3954-3962

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