Assessment of artemisinin and antioxidant activities of three wild Artemisia species of Algeria

被引：11

作者：

Ahmed-Laloui, Hamza ^{[1
]}

Zaak, Hadjer ^{[2
]}

Rahmani, Abderrahman ^{[1
]}

Kashi, Imad ^{[3
]}

Chemat, Smain ^{[4
]}

Miara, Mohamed Djamel ^{[6
]}

Cherb, Nora ^{[5
]}

Derdour, Mouna ^{[1
]}

机构：

[1] Biotechnol Res Ctr CRBt, Biotechnol & Agr Div, Anim Biotechnol Lab, Ali Mendjeli, Constantine, Algeria

[2] Biotechnol Res Ctr CRBt, Food Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[3] Biotechnol Res Ctr CRBt, Ind Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[4] Ctr Rech Sci & Tech Anal Physicochim CRAPC, Extract & Separat Tech Team, Algiers, Algeria

[5] Biotechnol Res Ctr CRBt, Environm Biotechnol Div, Ali Mendjeli, Constantine, Algeria

[6] Ibn Khaldoun Univ, Fac Nat & Life Sci, Dept Nat & Life Sci, Tiaret, Algeria

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 24期

关键词：

Artemisia; artemisinin; biological activities; crystallization; HPLC analysis; CHEMICAL-COMPOSITION; ANNUA L; ASSISTED EXTRACTION; ESSENTIAL OIL; ANTIBACTERIAL; PURIFICATION; ANTIFUNGAL; ULTRASOUND;

D O I：

10.1080/14786419.2022.2025803

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Artemisinin, a natural product, has received considerable attention in the last few years as a potent antimalarial drug. This study reports the presence of Artemisinin in three Algerian wild Artemisia species assessed by HPLC method: A. herba-alba (AH), A. campestris subsp. glutinosa (AC), and A. judaica subsp sahariensis (AJ). The HPLC analysis of the hexane extracts, showed a difference in artemisinin content in studied species with a yield of 0.64%, 0.34% and 0.04% for AC, AH and AJ, respectively. Moreover, the level of artemisinin obtained in A. campestris was better than those found in A. sieberi and A. annua. This rate has been reported for the first time. Furthermore, the antiradical activities of methanolic extracts of plants were also tested. There was a remarkable antioxidant capacity found in all Artemisia methanolic extracts analysed.

引用

页码：6344 / 6352

页数：9

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