Seizure outcome after functional hemispherectomy for malformations of cortical development

被引:59
作者
Carreño, M
Wyllie, E
Bingaman, W
Kotagal, P
Comair, Y
Ruggieri, P
机构
[1] Cleveland Clin Fdn, Dept Neurol, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA
[3] Cleveland Clin Fdn, Dept Neuroradiol, Cleveland, OH 44195 USA
关键词
D O I
10.1212/WNL.57.2.331
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
MRI features were correlated with postsurgical seizure outcome in patients with hemispheric malformations of cortical development (MCD). After functional hemispherectomy, 5 of 6 patients (83%) with hemimegalencephaly had persistent, although markedly improved, seizures; 5 of 6 patients (83%) with relative preservation of part of one lobe or atrophy were seizure free. Hemimegalencephaly and other types of hemispheric MCD appear to differ in prognosis for freedom from seizures after functional hemispherectomy.
引用
收藏
页码:331 / 333
页数:3
相关论文
共 9 条
[1]  
BARKOVICH AJ, 1990, AM J NEURORADIOL, V11, P523
[2]   Neuro-cognitive development and epilepsy outcome in children with surgically treated hemimegalencephaly [J].
Battaglia, D ;
Di Rocco, C ;
Iuvone, L ;
Acquafondata, C ;
Iannelli, A ;
Lettori, D ;
Guzzetta, F .
NEUROPEDIATRICS, 1999, 30 (06) :307-313
[3]   Bilateral neuropathologic changes in a child with hemimegalencephaly [J].
Jahan, R ;
Mischel, PS ;
Curran, JG ;
Peacock, WJ ;
Shields, DW ;
Vinters, HV .
PEDIATRIC NEUROLOGY, 1997, 17 (04) :344-349
[4]  
Maehara Taketoshi, 2000, No To Hattatsu, V32, P395
[5]   Postoperative seizure control and antiepileptic drug use in pediatric epilepsy surgery patients: The UCLA experience, 1986-1997 [J].
Mathern, GW ;
Giza, CC ;
Yudovin, S ;
Vinters, HV ;
Peacock, WJ ;
Shewmon, DA ;
Shields, WD .
EPILEPSIA, 1999, 40 (12) :1740-1749
[6]   HEMISPHERECTOMY FOR SEIZURES REVISITED [J].
RASMUSSEN, T .
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1983, 10 (02) :71-78
[7]   HEMIMEGALENCEPHALY AND INTRACTABLE EPILEPSY - BENEFITS OF HEMISPHERECTOMY [J].
VIGEVANO, F ;
BERTINI, E ;
BOLDRINI, R ;
BOSMAN, C ;
CLAPS, D ;
DICAPUA, M ;
DIROCCO, C ;
ROSSI, GF .
EPILEPSIA, 1989, 30 (06) :833-843
[8]   Why would you remove half a brain? The outcome of 58 children after hemispherectomy - The Johns Hopkins experience: 1968 to 1996 [J].
Vining, EPG ;
Freeman, JM ;
Pillas, DJ ;
Uematsu, S ;
Carson, BS ;
Brandt, J ;
Boatman, D ;
Pulsifer, MB ;
Zuckerberg, A .
PEDIATRICS, 1997, 100 (02) :163-171
[9]   Seizure outcome after epilepsy surgery in children and adolescents [J].
Wyllie, E ;
Comair, YG ;
Kotagal, P ;
Bulacio, J ;
Bingaman, W ;
Ruggieri, P .
ANNALS OF NEUROLOGY, 1998, 44 (05) :740-748