A Diffusion-Based pH Regulator in Laminar Flows with Smartphone-Based Colorimetric Analysis

被引：3

作者：

Wang, Wei ^{[1
]}

Zeng, Zhi ^{[1
]}

Xu, Wei ^{[1
]}

Wu, Wenming ^{[2
]}

Liang, Wenfeng ^{[3
]}

Zhou, Jia ^{[1
]}

机构：

[1] Fudan Univ, Sch Microelect, ASIC & Syst State Key Lab, Shanghai 200433, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Opt Fine Mech & Phys CIOMP, State Key Lab Appl Opt, Changchun 130033, Jilin, Peoples R China

[3] Shenyang Jianzhu Univ, Sch Mech Engn, Shenyang 110168, Liaoning, Peoples R China

来源：

MICROMACHINES | 2018年 / 9卷 / 12期

基金：

上海市自然科学基金; 中国国家自然科学基金; 美国国家科学基金会;

关键词：

pH regulator; diffusion; laminar flows; smartphone; colorimetric analysis; DEVICE; GENERATION; GRADIENTS; PLATFORM; ARRAY;

D O I：

10.3390/mi9120616

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A strategy for an on-chip pH regulator is demonstrated computationally and experimentally, based on the diffusion characteristics of aqueous ionic solutions. Micro-flows with specific pH values are formed based on the diffusion behaviors of hydrogen and hydroxide ions in laminar flows. The final achieved pH value and its gradient in the channel can be regulated by the amount of ions transported between laminar flows, and the experimental results can be further generalized based on the normalized Nernst-Planck equation. A smartphone was applied as an image capture and analysis instrument to quantify pH values of liquids in a colorimetric detection process, with monotonic response range of similar to 1-13.

引用

页数：11

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