NMR analysis of the chain microstructure of biodegradable terpolymers with shape memory properties

被引：27

作者：

Gebarowska, Katarzyna ^{[1
]}

Kasperczyk, Janusz ^{[1
,2
]}

Dobrzynski, Piotr ^{[1
,3
]}

Scandola, Mariastella ^{[4
,5
]}

Zini, Elisa ^{[4
,5
]}

Li, Suming ^{[6
]}

机构：

[1] Polish Acad Sci, Ctr Polymer & Carbon Mat, PL-41800 Zabrze, Poland

[2] Med Univ Silesia, Sch Pharm, Dept Biopharm, PL-41200 Sosnowiec, Poland

[3] Jan Dlugosz Univ Czestochowa, Inst Chem, Inst Chem Environm Protect & Biotechnol, PL-42218 Czestochowa, Poland

[4] Univ Bologna, Dept Chem G Ciamician, I-40126 Bologna, Italy

[5] INSTM UdR Bologna, I-40126 Bologna, Italy

[6] Univ Montpellier I, Res Ctr Artificial Biopolymers, Fac Pharm, F-34060 Montpellier, France

来源：

EUROPEAN POLYMER JOURNAL | 2011年 / 47卷 / 06期

关键词：

(Glycolide-L-lactide-trimethylene carbonate) terpolymers; Shape-memory; Microstructure; NMR; TOXICITY ZIRCONIUM COMPOUNDS; RING-OPENING POLYMERIZATION; L-LACTIDE; EPSILON-CAPROLACTONE; HYDROLYTIC DEGRADATION; TRIMETHYLENE CARBONATE; SEQUENCE DISTRIBUTION; COPOLYMERS; GLYCOLIDE; C-13;

D O I：

10.1016/j.eurpolymj.2011.02.022

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Terpolymers of lactide, glycolide and trimethylene carbonate initiated on zirconium acetylacetonate (IV) exhibit shape-memory behaviors in the range of body temperature when appropriate monomer composition and characterizing conditions are applied. In this paper, the procedure of characterizing these terpolymers by means of nuclear magnetic resonance spectroscopy is presented. The H-1 and C-13 NMR spectra allow to characterize the chain microstructure of these polyester-carbonates in spite of overlapping resonance signals due to the possibility of forming different co-monomeric sequences. Detailed assignment was given for spectral lines in proton and carbon spectra recorded in polar and non-polar deuterated solvents. For quantitative analysis, equations for calculations of average block lengths, long and mixed glycolidyl, lactidyl and carbonate blocks as well as formulas allowing to investigate intramolecular transestrification processes were elaborated. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1315 / 1327

页数：13

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