Osteopenia of prematurity: a national survey and review of practice

被引:90
作者
Harrison, C. M. [1 ,2 ]
Johnson, K. [1 ]
McKechnie, E. [1 ]
机构
[1] Leeds Gen Infirmary, Peter Congdon Neonatal Unit, Leeds LS2 9NS, W Yorkshire, England
[2] Leeds Teaching Hosp, Dept Neonatol, Leeds, W Yorkshire, England
关键词
bone mineralization; osteopenia; rickets;
D O I
10.1111/j.1651-2227.2007.00721.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Premature infants are at significant risk of reduced bone mineral content (BMC) and subsequent osteopenia. There are currently no standard practices regarding screening, investigation or treatment of this condition. We present a case report and findings of a national survey of 36 level 2 and 3 neonatal units (72% response rate). The findings showed widely disparate practice regarding screening, prevention and treatment. We summarize the tests currently available for osteopenia and suggest guidelines for management of the at risk group. Conclusion: Our survey confirms inconsistent practices regarding management of infants at risk of osteopenia of prematurity. Investigations and treatments available are summarized together with a guideline for management of this susceptible group of infants.
引用
收藏
页码:407 / 413
页数:7
相关论文
共 43 条
[11]   Spontaneous activity in premature infants affects bone strength [J].
Eliakim A. ;
Nemet D. ;
Friedland O. ;
Dolfin T. ;
Regev R.H. .
Journal of Perinatology, 2002, 22 (8) :650-652
[12]   Bone mineralisation in premature infants cannot be predicted from serum alkaline phosphatase or serum phosphate [J].
Faerk, J ;
Peitersen, B ;
Petersen, S ;
Michaelsen, KF .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2002, 87 (02) :F133-F136
[13]   RACHITIC RESPIRATORY-DISTRESS IN SMALL PRETERM INFANTS [J].
GLASGOW, JFT ;
THOMAS, PS .
ARCHIVES OF DISEASE IN CHILDHOOD, 1977, 52 (04) :268-273
[14]   Renal phosphate handling of premature infants of 23-25 weeks gestational age [J].
Hellstern, G ;
Pöschl, J ;
Linderkamp, O .
PEDIATRIC NEPHROLOGY, 2003, 18 (08) :756-758
[15]   PRENATAL DEFICIENCY OF PHOSPHATE, PHOSPHATE SUPPLEMENTATION, AND RICKETS IN VERY-LOW-BIRTH-WEIGHT INFANTS [J].
HOLLAND, PC ;
WILKINSON, AR ;
DIEZ, J ;
LINDSELL, DRM .
LANCET, 1990, 335 (8691) :697-701
[16]   OSTEOPENIA IN EXTREMELY LOW-BIRTH-WEIGHT INFANTS [J].
HORSMAN, A ;
RYAN, SW ;
CONGDON, PJ ;
TRUSCOTT, JG ;
JAMES, JR .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1989, 64 (04) :485-488
[17]  
KOVAR I, 1982, LANCET, V1, P308
[18]  
Kuschel CA., 2004, Cochrane Database of Systematic Reviews, P1, DOI 10.1002/14651858.CD000343
[19]   Bone turnover markers and bone strength during the first weeks of life in very low birth weight premature infants [J].
Litmanovitz, I ;
Dolfin, T ;
Regev, R ;
Arnon, S ;
Friedland, O ;
Shainkin-Kestenbaum, R ;
Lis, M ;
Eliakim, A .
JOURNAL OF PERINATAL MEDICINE, 2004, 32 (01) :58-61
[20]  
Littner Y, 2003, J PEDIATR ENDOCR MET, V16, P43