Preparation of unsymmetrical distyryl BODIPY derivatives and effects of the styryl substituents on their in vitro photodynamic properties

被引：88

作者：

He, Hui ^{[1
]}

Lo, Pui-Chi ^{[1
]}

Yeung, Sin-Lui ^{[2
]}

Fong, Wing-Ping ^{[2
]}

Ng, Dennis K. P. ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Sch Life Sci, Shatin, Hong Kong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 16期

关键词：

SENSITIZED SOLAR-CELLS; EFFICIENT PHOTOSENSITIZERS; ENERGY-TRANSFER; THERAPY; CANCER; BORADIAZAINDACENES; LOGIC; DYES;

D O I：

10.1039/c1cc10727e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of unsymmetrical distyryl BODIPYs have been prepared which function as highly potent photosensitisers with in vitro IC50 values as low as 15 nM. Their cellular uptake, subcellular localisation and photocytotoxicity depend greatly on the styryl substituents.

引用

页码：4748 / 4750

页数：3

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