Clinical infrared microscopic imaging: An overview

被引：14
作者：
Pallua, J. D. [1 ,2 ]
Brunner, A. [1 ]
Zelger, B. [1 ]
Stalder, R. [3 ]
Unterberger, S. H. [4 ]
Schirmer, M. [5 ]
Tappert, M. C. [6 ]
机构：
[1] Med Univ Innsbruck, Dept Pathol, Mullerstr 44, A-6020 Innsbruck, Austria
[2] Med Univ Innsbruck, Inst Legal Med, Mullerstr 44, A-6020 Innsbruck, Austria
[3] Leopold Franzens Univ Innsbruck, Inst Mineral & Petrog, Innrain 52, A-6020 Innsbruck, Austria
[4] Leopold Franzens Univ Innsbruck, Mat Technol, Technikerstr 13, A-6020 Innsbruck, Austria
[5] Med Univ Innsbruck, Dept Internal Med, Clin 2, Anichstr 35, A-6020 Innsbruck, Austria
[6] Hyperspectral Intelligence Inc, Box 851, Gibsons, BC V0N 1V0, Canada
来源：
PATHOLOGY RESEARCH AND PRACTICE | 2018年 / 214卷 / 10期
关键词：
Mid-infrared microscopic imaging; Molecular fingerprint; Chemical as well as physical sample properties; Statistical classification; Three-dimensional image data cube; Histopathology; HUMAN TISSUE; IR SPECTROSCOPY; MICRO-SPECTROSCOPY; COLON-CANCER; MICROSPECTROSCOPY; RAMAN; FTIR; CELLS; CLASSIFICATION; DIAGNOSIS;
D O I：
10.1016/j.prp.2018.08.026
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
New developments in Mid-infrared microscopic imaging instrumentation and data analysis have turned this method into a conventional technique. This imaging method offers a global analysis of samples, with a resolution close to the cellular level enabling the acquisition of local molecular expression profiles. It is possible to get chemo-morphological information about the tissue status, which represents an essential benefit for future analytical interpretation of pathological changes of tissue. In this review, we give an overview of Mid-infrared microscopic imaging and its applications in clinical research.
引用
收藏
页码：1532 / 1538
页数：7
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