Clinical infrared microscopic imaging: An overview

被引：14

作者：

Pallua, J. D. ^{[1
,2
]}

Brunner, A. ^{[1
]}

Zelger, B. ^{[1
]}

Stalder, R. ^{[3
]}

Unterberger, S. H. ^{[4
]}

Schirmer, M. ^{[5
]}

Tappert, M. C. ^{[6
]}

机构：

[1] Med Univ Innsbruck, Dept Pathol, Mullerstr 44, A-6020 Innsbruck, Austria

[2] Med Univ Innsbruck, Inst Legal Med, Mullerstr 44, A-6020 Innsbruck, Austria

[3] Leopold Franzens Univ Innsbruck, Inst Mineral & Petrog, Innrain 52, A-6020 Innsbruck, Austria

[4] Leopold Franzens Univ Innsbruck, Mat Technol, Technikerstr 13, A-6020 Innsbruck, Austria

[5] Med Univ Innsbruck, Dept Internal Med, Clin 2, Anichstr 35, A-6020 Innsbruck, Austria

[6] Hyperspectral Intelligence Inc, Box 851, Gibsons, BC V0N 1V0, Canada

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2018年 / 214卷 / 10期

关键词：

Mid-infrared microscopic imaging; Molecular fingerprint; Chemical as well as physical sample properties; Statistical classification; Three-dimensional image data cube; Histopathology; HUMAN TISSUE; IR SPECTROSCOPY; MICRO-SPECTROSCOPY; COLON-CANCER; MICROSPECTROSCOPY; RAMAN; FTIR; CELLS; CLASSIFICATION; DIAGNOSIS;

D O I：

10.1016/j.prp.2018.08.026

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

New developments in Mid-infrared microscopic imaging instrumentation and data analysis have turned this method into a conventional technique. This imaging method offers a global analysis of samples, with a resolution close to the cellular level enabling the acquisition of local molecular expression profiles. It is possible to get chemo-morphological information about the tissue status, which represents an essential benefit for future analytical interpretation of pathological changes of tissue. In this review, we give an overview of Mid-infrared microscopic imaging and its applications in clinical research.

引用

页码：1532 / 1538

页数：7

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