ANALYSIS OF BLOOD GLUCOSE DYNAMICS IN LIVER TRANSPLANTATION: A MODEL-BASED APPROACH

被引：0

作者：

Homlok, J. ^{[1
]}

Chase, J. G. ^{[2
]}

Doktor, T. ^{[1
]}

Benyo, B. ^{[1
]}

机构：

[1] Budapest Univ Technol & Econ, Dept Control Engn & Informat Technol, Budapest, Hungary

[2] Univ Canterbury, Dept Mech Engn, Christchurch, New Zealand

来源：

BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK | 2014年 / 59卷

关键词：

liver-transplantation; blood glucose dynamics; model-based analysis;

D O I：

10.1515/bmt-2014-4395

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A safe, effective glycemic control would have beneficial effects on the outcomes of liver transplantation (LT) patients. The model-based validated glycemic control protocol, STAR, is proven for ICU patients. However, the ICING model used for STAR differs in the blood glucose dynamics compared to the LT patients who have no liver for part of the surgery. By localizing the places of extraordinary LT patient's dynamics we can specify modifications for the ICU patient model. These dynamics mainly occur in the: 1) pre-anhepatic phase at the beginning of the surgery; 2) at the portal vein reperfusion; and 3) in the post-anhepatic phase before 500 minutes after the reperfusion.

引用

页码：S923 / +

页数：4

共 22 条

[1] Effect of intraoperative hyperglycemia during liver transplantation [J].

Ammori, John B. ;

Sigakis, Matthew ;

Englesbe, Michael J. ;

O'Reilly, Michael ;

Pelletier, Shawn J. .

JOURNAL OF SURGICAL RESEARCH, 2007, 140 (02) :227-233

[2]

Benyo B., 2013, MINIMALLY INVASIV S1, V22, P24

[3] Comparison of Three Protocols for Tight Glycemic Control in Cardiac Surgery Patients [J].

Blaha, Jan ;

Kopecky, Petr ;

Matias, Michal ;

Hovorka, Roman ;

Kunstyr, Jan ;

Kotulak, Tomas ;

Lips, Michal ;

Rubes, David ;

Stritesky, Martin ;

Lindner, Jaroslav ;

Semrad, Michal ;

Haluzik, Martin .

DIABETES CARE, 2009, 32 (05) :757-761

[4] Validation of a model-based virtual trials method for tight glycemic control in intensive care [J].

Chase, J. Geoffrey ;

Suhaimi, Fatanah ;

Penning, Sophie ;

Preiser, Jean-Charles ;

Le Compte, Aaron J. ;

Lin, Jessica ;

Pretty, Christopher G. ;

Shaw, Geoffrey M. ;

Moorhead, Katherine T. ;

Desaive, Thomas .

BIOMEDICAL ENGINEERING ONLINE, 2010, 9

[5] External validation and sub-cohort analysis of stochastic forecasting models in NICU cohorts [J].

Dickson, Jennifer L. ;

Floyd, Richard P. ;

Le Compte, Aaron J. ;

Fisk, Liam M. ;

Chase, J. Geoffrey ;

Lynn, Adrienne ;

Shaw, Geoffrey M. .

BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 2013, 8 (04) :409-419

[6] Development and optimisation of stochastic targeted (STAR) glycaemic control for pre-term infants in neonatal intensive care [J].

Dickson, Jennifer L. ;

Le Compte, Aaron J. ;

Floyd, Richard P. ;

Chase, J. Geoffrey ;

Lynn, Adrienne ;

Shaw, Geoffrey M. .

BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 2013, 8 (02) :215-221

[7] Variability of blood glucose concentration and short-term mortality in ctitically ill patients [J].

Egi, Moritoki ;

Bellomo, Rinaldo ;

Stachowski, Edward ;

French, Craig J. ;

Hart, Graerne .

ANESTHESIOLOGY, 2006, 105 (02) :244-252

[8] STAR Development and Protocol Comparison [J].

Fisk, Liam M. ;

Le Compte, Aaron J. ;

Shaw, Geoffrey M. ;

Penning, Sophie ;

Desaive, Thomas ;

Chase, J. Geoffrey .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2012, 59 (12) :3357-3364

[9]

Homlok Jozsef, 2013, 2013 IEEE 17th International Conference on Intelligent Engineering Systems (INES), P65, DOI 10.1109/INES.2013.6632784

[10]

Homlok J., 2013, MINIMALLY INVASIV S1, V22, P23

← 1 2 3 →