Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside-protein complex

被引：33
作者：
Bond, Michelle R. [1 ,2 ]
Whitman, Chad M. [1 ,2 ]
Kohler, Jennifer J. [1 ]
机构：
[1] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Div Translat Res, Dallas, TX 75390 USA
[2] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
来源：
MOLECULAR BIOSYSTEMS | 2010年 / 6卷 / 10期
基金：
美国国家卫生研究院;
关键词：
RECOGNIZING PROTEINS; GLYCOSPHINGOLIPIDS; BINDING; CELLS; CONVERSION; INHIBITOR; GM3;
D O I：
10.1039/c0mb00069h
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
When photoirradiated, an unnatural sialic acid analog can covalently capture the complex formed by ganglioside GM1 and cholera toxin subunit B.
引用
收藏
页码：1796 / 1799
页数：4
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