Homeopathy: Clarifying its relationship to hormesis

被引:31
作者
Calabrese, Edward J. [1 ]
Jonas, Wayne B. [2 ]
机构
[1] Univ Massachusetts, Sch Publ Hlth, Environm Hlth Sci Program, Amherst, MA 01003 USA
[2] Samueli Inst, Alexandria, VA USA
关键词
homeopathy; hormesis; dose-response; overcompensation; tissue repair; stress response; STRESS-RESPONSE; DOSE RESPONSES; MINUTE AMOUNTS; STIMULATION; ENHANCEMENT; IMMUNOLOGY; CELLS;
D O I
10.1177/0960327110369857
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
This paper presents the case that certain types of homeopathic medicine may represent a form of hormesis, that is, either pre- or post-conditioning hormesis. An example of a post-conditioning model by van Wijk and colleagues demonstrated successful enhancement of adaptive responses using below-toxic threshold doses (i.e. hormetic doses) of inducing agents when administered subsequent to a highly toxic chemical exposure, thus satisfying a basic experimental biomedical standard. Of note is that this model uses exposures within a measurable predicted hormetic range, unlike most forms of homeopathy. This experimental framework (along with a pre-conditioning model developed by Bellavite) provides a possible vehicle by which certain aspect(s) of homeopathy may be integrated into mainstream biomedical assessment and clinical practice.
引用
收藏
页码:531 / 536
页数:6
相关论文
共 26 条
[1]  
ANICK D, 2007, J HOMEOPATHY, V96, P186
[2]  
BELLAVITE P, 2003, J HOMEOPATHY, V94, P203
[3]   Immunology and homeopathy. 4. Clinical studies - Part 2 [J].
Bellavite, Paolo ;
Ortolani, Riccardo ;
Pontarollo, Francesco ;
Piasere, Valeria ;
Benato, Giovanni ;
Conforti, Anita .
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2006, 3 (04) :397-409
[4]   Immunology and homeopathy.: 5.: The rationale of the 'Simile' [J].
Bellavite, Paolo ;
Ortolani, Riccardo ;
Pontarollo, Francesco ;
Pitari, Giuseppina ;
Conforti, Anita .
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2007, 4 (02) :149-163
[5]  
Bohme H., 1986, THESIS FREIEN U BERL
[6]   The effects of certain chemical compounds upon the course of gas production by baker's yeast [J].
Branham, SE .
JOURNAL OF BACTERIOLOGY, 1929, 18 (04) :247-264
[7]  
Calabrese EJ, 2008, ENVIRON TOXICOL CHEM, V27, P1451, DOI 10.1897/07-541
[8]   Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework [J].
Calabrese, Edward J. ;
Bachmann, Kenneth A. ;
Bailer, A. John ;
Bolger, P. Michael ;
Borak, Jonathan ;
Cai, Lu ;
Cedergreen, Nina ;
Cherian, M. George ;
Chiueh, Chuang C. ;
Clarkson, Thomas W. ;
Cook, Ralph R. ;
Diamond, David M. ;
Doolittle, David J. ;
Dorato, Michael A. ;
Duke, Stephen O. ;
Feinendegen, Ludwig ;
Gardner, Donald E. ;
Hart, Ronald W. ;
Hastings, Kenneth L. ;
Hayes, A. Wallace ;
Hoffmann, George R. ;
Ives, John A. ;
Jaworowski, Zbigniew ;
Johnson, Thomas E. ;
Jonas, Wayne B. ;
Kaminski, Norbert E. ;
Keller, John G. ;
Klaunig, James E. ;
Knudsen, Thomas B. ;
Kozumbo, Walter J. ;
Lettleri, Teresa ;
Liu, Shu-Zheng ;
Maisseu, Andre ;
Maynard, Kenneth I. ;
Masoro, Edward J. ;
McClellan, Roger O. ;
Mehendale, Harlhara M. ;
Mothersill, Carmel ;
Newlin, David B. ;
Nigg, Herbert N. ;
Oehme, Frederick W. ;
Phalen, Robert F. ;
Philbert, Martin A. ;
Rattan, Suresh I. S. ;
Riviere, Jim E. ;
Rodricks, Joseph ;
Sapolsky, Robert M. ;
Scott, Bobby R. ;
Seymour, Colin ;
Sinclair, David A. .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2007, 222 (01) :122-128
[9]   Cancer biology and hormesis: Human tumor cell lines commonly display hormetic (biphasic) dose responses [J].
Calabrese, EJ .
CRITICAL REVIEWS IN TOXICOLOGY, 2005, 35 (06) :463-582
[10]   The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview [J].
Calabrese, EJ ;
Blain, R .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2005, 202 (03) :289-301