Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho [2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives

被引:6
作者
Gaikwad, Sanjeevan S. [1 ]
Suryawanshi, Venkat S. [2 ]
Lohar, Kishan S. [1 ]
Jadhav, Dhanaji V. [3 ]
Shinde, Narayan D. [2 ]
机构
[1] Shrikrishna Coll, Dept Chem, Tal Omerga 413613, Maharashtra, India
[2] Shri Chattrapati Shivaji Coll, Dept Chem, PG Studies & Res Ctr, Omerga 413606, Maharashtra, India
[3] YC Arts & Sci Coll, Dept Chem, Mangrulpir 444403, Maharashtra, India
关键词
Naphthofuran; Chalcone; Oxopyrimidines; Synthesis; Biological activities; AGENTS;
D O I
10.1155/2012/258672
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, H-1 NMR, mass spectral data and elemental analysis. The synthesized oxopyrimidines derivatives were evaluated for antibacterial and antifungal activities, some of them were found to possess significant activity.
引用
收藏
页码:175 / 180
页数:6
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