Novel techniques in the use of bivalirudin for cardiopulmonary bypass anticoagulation in a child with heparin-induced thrombocytopenia
被引:11
作者:
Dragomer, D.
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机构:
Univ Calif Los Angeles, Perfus Serv, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
Dragomer, D.
[2
]
Chalfant, A.
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机构:
Univ Calif Los Angeles, Perfus Serv, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
Chalfant, A.
[2
]
Biniwale, R.
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机构:Univ Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
Biniwale, R.
Reemtsen, B.
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机构:Univ Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
Reemtsen, B.
Federman, M.
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Univ Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
Federman, M.
[1
]
机构:
[1] Univ Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Perfus Serv, Los Angeles, CA 90095 USA
Heparin-induced thrombocytopenia (HIT) occurs in both the pediatric and adult populations after exposure to heparin. Bivalirudin has been used as an alternative to heparin for adults undergoing cardiac surgery and cardiopulmonary bypass, but has only been used minimally in children for this purpose. We report the successful use of bivalirudin for anticoagulation during cardiopulmonary bypass in a small child with HIT, using novel techniques not previously described.