Novel techniques in the use of bivalirudin for cardiopulmonary bypass anticoagulation in a child with heparin-induced thrombocytopenia

被引:11
作者
Dragomer, D. [2 ]
Chalfant, A. [2 ]
Biniwale, R.
Reemtsen, B.
Federman, M. [1 ]
机构
[1] Univ Calif Los Angeles, Div Pediat Crit Care, Mattel Childrens Hosp, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Perfus Serv, Los Angeles, CA 90095 USA
来源
PERFUSION-UK | 2011年 / 26卷 / 06期
关键词
cardiopulmonary bypass; heparin; bivalirudin; anticoagulation; pediatric;
D O I
10.1177/0267659111419037
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heparin-induced thrombocytopenia (HIT) occurs in both the pediatric and adult populations after exposure to heparin. Bivalirudin has been used as an alternative to heparin for adults undergoing cardiac surgery and cardiopulmonary bypass, but has only been used minimally in children for this purpose. We report the successful use of bivalirudin for anticoagulation during cardiopulmonary bypass in a small child with HIT, using novel techniques not previously described.
引用
收藏
页码:516 / 518
页数:3
相关论文
共 7 条
  • [1] Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia
    Almond, Christopher S. D.
    Harrington, James
    Thiagarajan, Ravi
    Duncan, Christine N.
    LaPierre, Robert
    Halwick, David
    Blume, Elizabeth D.
    Del Nido, Pedro J.
    Neufeld, Ellis J.
    McGowan, Francis X.
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (11) : 1376 - 1379
  • [2] The Use of Bivalirudin for Cardiopulmonary Bypass Anticoagulation in Pediatric Heparin-Induced Thrombocytopenia Patients
    Gates, Richard
    Yost, Paul
    Parker, Beth
    [J]. ARTIFICIAL ORGANS, 2010, 34 (08) : 667 - U2
  • [3] Assessment of hemostatic activation during cardiopulmonary bypass for coronary artery bypass grafting with bivalirudin: Results of a pilot study
    Koster, A
    Yeter, R
    Buz, S
    Kuppe, H
    Hetzer, R
    Lincoff, AM
    Dyke, CM
    Smedira, NG
    Spiess, B
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2005, 129 (06) : 1391 - 1394
  • [4] Bivalirudin anticoagulation during cardiac surgery: a single-center experience in 141 patients
    Koster, A.
    Buz, S.
    Krabatsch, T.
    Yeter, R.
    Hetzer, R.
    [J]. PERFUSION-UK, 2009, 24 (01): : 7 - 11
  • [5] Diagnosis and treatment of heparin-induced thrombocytopenia in neonates and children
    Risch, Lorenz
    Huber, Andreas R.
    Schmugge, Markus
    [J]. THROMBOSIS RESEARCH, 2006, 118 (01) : 123 - 135
  • [6] Heparin-induced thrombocytopenia and cardiac surgery (vol 76, pg 638, 2003)
    Warkentin, TE
    Greinacher, A
    [J]. ANNALS OF THORACIC SURGERY, 2003, 76 (06) : 2121 - 2131
  • [7] Heparin-induced thrombocytopenia: pathogenesis and management
    Warkentin, TE
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2003, 121 (04) : 535 - 555