COVID-19: Emergence, Spread, Possible Treatments, and Global Burden

被引:135
|
作者
Keni, Raghuvir [1 ]
Alexander, Anila [2 ]
Nayak, Pawan Ganesh [1 ]
Mudgal, Jayesh [1 ]
Nandakumar, Krishnadas [1 ]
机构
[1] Manipal Acad Higher Educ, Manipal Coll Pharmaceut Sci, Dept Pharmacol, Manipal, India
[2] Cape Breton Univ, Sch Educ & Hlth, Dept Hlth Sci, Sydney, NS, Canada
关键词
2019-nCoV; COVID-19; SARS-CoV-2; coronavirus; pandemic; SARS; THERAPEUTIC-EFFICACY; RESPIRATORY SYNDROME; CORONAVIRUS; SARS; REPLICATION; REMDESIVIR; RESERVOIRS; PNEUMONIA; 2019-NCOV; DISEASE;
D O I
10.3389/fpubh.2020.00216
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The Coronavirus (CoV) is a large family of viruses known to cause illnesses ranging from the common cold to acute respiratory tract infection. The severity of the infection may be visible as pneumonia, acute respiratory syndrome, and even death. Until the outbreak of SARS, this group of viruses was greatly overlooked. However, since the SARS and MERS outbreaks, these viruses have been studied in greater detail, propelling the vaccine research. On December 31, 2019, mysterious cases of pneumonia were detected in the city of Wuhan in China's Hubei Province. On January 7, 2020, the causative agent was identified as a new coronavirus (2019-nCoV), and the disease was later named as COVID-19 by the WHO. The virus spread extensively in the Wuhan region of China and has gained entry to over 210 countries and territories. Though experts suspected that the virus is transmitted from animals to humans, there are mixed reports on the origin of the virus. There are no treatment options available for the virus as such, limited to the use of anti-HIV drugs and/or other antivirals such as Remdesivir and Galidesivir. For the containment of the virus, it is recommended to quarantine the infected and to follow good hygiene practices. The virus has had a significant socio-economic impact globally. Economically, China is likely to experience a greater setback than other countries from the pandemic due to added trade war pressure, which have been discussed in this paper.
引用
收藏
页数:13
相关论文
共 50 条
  • [21] COVID-19 and Cancer: a Comprehensive Review
    Gosain, Rohit
    Abdou, Yara
    Singh, Abhay
    Rana, Navpreet
    Puzanov, Igor
    Ernstoff, Marc S.
    CURRENT ONCOLOGY REPORTS, 2020, 22 (05)
  • [22] The Predictive Capacity of Air Travel Patterns during the Global Spread of the COVID-19 Pandemic: Risk, Uncertainty and Randomness
    Christidis, Panayotis
    Christodoulou, Aris
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2020, 17 (10)
  • [23] Current Therapeutic Interventions for COVID-19
    Arsoy, Hacer Efnan Melek
    Ozdemir, Oner
    BEZMIALEM SCIENCE, 2020, 8 : 105 - 116
  • [24] The Politics of Pandemic Othering: Putting COVID-19 in Global and Historical Context
    Dionne, Kim Yi
    Turkmen, Fulya Felicity
    INTERNATIONAL ORGANIZATION, 2020, 74 : E213 - E230
  • [25] The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic
    Kumar, Rajesh
    Harilal, Seetha
    Al-Sehemi, Abdullah G.
    Mathew, Githa Elizabeth
    Carradori, Simone
    Mathew, Bijo
    CURRENT MEDICINAL CHEMISTRY, 2021, 28 (15) : 2852 - 2886
  • [26] The effects of regional climatic condition on the spread of COVID-19 at global scale
    Iqbal, Muhammad Mazhar
    Abid, Irfan
    Hussain, Saddam
    Shahzad, Naeem
    Waqas, Muhammad Sohail
    Iqbal, Muhammad Jawed
    SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 739
  • [27] Clinical Insights into the Gastrointestinal Manifestations of COVID-19
    Kopel, Jonathan
    Perisetti, Abhilash
    Gajendran, Mahesh
    Boregowda, Umesha
    Goyal, Hemant
    DIGESTIVE DISEASES AND SCIENCES, 2020, 65 (07) : 1932 - 1939
  • [28] COVID-19: benefits and risks of passive immunotherapeutics
    Gupta, Ankur
    Karki, Rashmi
    Dandu, Himanshu R.
    Dhama, Kuldeep
    Bhatt, Madan L. B.
    Saxena, Shailendra K.
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2020, 16 (12) : 2963 - 2972
  • [29] Chloroquine and COVID-19 a potential game changer?
    Sturrock, Beattie R. H.
    Chevassut, Timothy J. T.
    CLINICAL MEDICINE, 2020, 20 (03) : 278 - 281
  • [30] Early Research on COVID-19: A Bibliometric Analysis
    Gong, Yue
    Ma, Ting-Can
    Xu, Yang-Yang
    Yang, Rui
    Gao, Lan-Jun
    Wu, Si-Hua
    Li, Jing
    Yue, Ming-Liang
    Liang, Hui-Gang
    He, Xiao
    Yun, Tao
    INNOVATION, 2020, 1 (02):