Diagnosis of congenital toxoplasmosis by polymerase chain reaction on neonatal peripheral blood

被引:19
作者
Sterkers, Yvon [1 ]
Ribot, Jennifer
Albaba, Sahar
Issert, Eric
Bastien, Patrick
Pratlong, Francine
机构
[1] Univ Hosp Ctr Montpellier, Fac Med, Dept Parasitol Mycol, Montpellier, France
关键词
Toxoplasma gondii; PCR; Amniotic fluid; Placenta; Cord blood; MOLECULAR-DETECTION; GONDII INFECTION; AMNIOTIC-FLUID; AMPLIFICATION; PERFORMANCE;
D O I
10.1016/j.diagmicrobio.2011.06.006
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In a cohort of 12 consecutive neonates, polymerase chain reaction (PCR) established the diagnosis of 5 of 6 cases of congenital toxoplasmosis and did so earlier than serologic methods. We validated that PCR using neonatal peripheral blood is a sensitive, rapid, and cost-effective method to affirm the diagnosis of previously undiagnosed congenital toxoplasmosis. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:174 / 176
页数:3
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