Synthesis of some novel oxazolopyranoquinolinones from 3-amino-4-hydroxypyrano[3,2-c]quinolinedione

被引：7

作者：

Hassanin, Hany M. ^{[1
]}

Abdou, Ibrahim M. ^{[2
]}

Saeed, Abdeltawab M. ^{[1
,2
]}

机构：

[1] Ain Shams Univ Roxy, Fac Educ, Dept Chem, Cairo 11711, Egypt

[2] UAE Univ, Coll Sci, Dept Chem, Al Ain 15551, U Arab Emirates

来源：

ARKIVOC | 2017年

关键词：

Tin reduction; oxazole; pyran; quinolinone; heterocyclization; BIOLOGICAL-ACTIVITY; NATURAL-PRODUCTS; OXAZOLE; DERIVATIVES; AGENTS; ANTIBACTERIAL; REDUCTION; EFFICIENT; DESIGN;

D O I：

10.24820/ark.5550190.p010.196

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

6-n-Butyl-3-nitropyrano[3,2-c] quinolinone was chemoselectively reduced to an amine derivative in a good yield (70%) using an efficient and simple tin-hydrochloric acid reaction. The novel 3-aminopyranoquinolinone was utilized as a precursor to produce some new interesting tetracyclic fused oxazolopyranoquinolinone analogues. The structures of the obtained quinolinone derivatives were confirmed using IR, LC-MS, ESI-MS and NMR techniques.

引用

页码：172 / 186

页数：15

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