On the possibility of silicon nitride as a ceramic for structural orthopaedic implants. Part I: processing, microstructure, mechanical properties, cytotoxicity

被引:109
作者
Mazzocchi, Mauro [1 ]
Bellosi, Alida [1 ]
机构
[1] CNR, Inst Sci & Technol Ceram, I-48018 Faenza, Ravenna, Italy
关键词
D O I
10.1007/s10856-008-3417-2
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Notwithstanding the good combination of mechanical and tribological properties, the suitability of silicon nitride for application as prosthesis in bone reconstruction or in articular joints replacements is still controversial. This study aims to design and produce three different silicon nitride-based ceramics and to test the materials. In this Part I the microstructure and mechanical properties evidence outstanding characteristics and the cytotoxicity studies confirm that all the materials are extremely inert and biocompatible. In Part II, the wear performance and the wettability and chemical stability against different aqueous media and physiological solutions are investigated and discussed.
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页码:2881 / 2887
页数:7
相关论文
共 42 条
[1]   WEAR PROPERTIES OF SI3N4 IN ROLLING-SLIDING CONTACT [J].
AKAZAWA, M ;
KATO, K .
WEAR, 1988, 124 (02) :123-132
[2]   Improvement in zirconia osseointegration by means of a biological glass coating:: An in vitro and in vivo investigation [J].
Aldini, NN ;
Fini, M ;
Giavaresi, G ;
Torricelli, P ;
Martin, L ;
Giardino, R ;
Ravaglioli, A ;
Krajewski, A ;
Mazzocchi, M ;
Dubini, B ;
Ponzi-Bossi, MG ;
Rustichelli, F ;
Stanic, V .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 2002, 61 (02) :282-289
[3]   Densification route and mechanical properties of Si3N4-bioglass biocomposites [J].
Amaral, M ;
Lopes, MA ;
Silva, RF ;
Santos, JD .
BIOMATERIALS, 2002, 23 (03) :857-862
[4]  
BELLOSI A, 1992, J EUROP CERAM SOC, P983
[5]  
BELLOSI A, 1999, DESIGN PROCESSING NO, P285
[6]   Influence of powder characteristics and powder processing routes on microstructure and properties of hot pressed silicon nitride materials [J].
Bondanini, A ;
Monteverde, F ;
Bellosi, A .
JOURNAL OF MATERIALS SCIENCE, 2001, 36 (20) :4851-4862
[7]  
Diaz R. L., 2004, US Patent, Patent No. [0220679A1, 0220679]
[8]  
Fukura I., 1987, US Patent, Patent No. [4.636.218, 4636218]
[9]   Characterization of proteins and fibroblasts on thin inorganic films [J].
Giannoulis, CS ;
Desai, TA .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2002, 13 (01) :75-80
[10]   DENSIFICATION AND CHARACTERISTICS OF TIN CERAMICS [J].
GRAZIANI, T ;
BELLOSI, A .
JOURNAL OF MATERIALS SCIENCE LETTERS, 1995, 14 (15) :1078-1081