Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker

被引：9
|
作者：
Liu, Xingfen [1 ,2 ]
Shi, Lin [1 ,2 ]
Zhang, Zhiyong [1 ,2 ]
Fan, Quli [1 ,2 ]
Huang, Yanqin [1 ,2 ]
Su, Shao [1 ,2 ]
Fan, Chunhai [3 ]
Wang, Lianhui [1 ,2 ]
Huang, Wei [1 ,2 ,4 ,5 ]
机构：
[1] Nanjing Univ Posts & Telecommun, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Key Lab Organ Elect & Informat Displays, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ Posts & Telecommun, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Inst Adv Mat, Nanjing 210023, Jiangsu, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
[4] Nanjing Tech Univ Nanjing Tech, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Key Lab Flexible Elect, Nanjing 211816, Jiangsu, Peoples R China
[5] Nanjing Tech Univ Nanjing Tech, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Inst Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
来源：
ANALYST | 2015年 / 140卷 / 06期
基金：
中国国家自然科学基金;
关键词：
ALPHA-FETOPROTEIN; SENSITIVE DETECTION; NONSPECIFIC INTERACTIONS; MULTIPLEXED DETECTION; MOLECULAR BRUSH; ENERGY-TRANSFER; CANCER MARKERS; PROTEINS; IMMUNOASSAY; BIOSENSOR;
D O I：
10.1039/c4an02384f
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Highly charged nanoparticles of a conjugated polyelectrolyte brush were used to sense the human alpha-fetoprotein (AFP) by observing selective superquenching in several minutes. The unique property of nanoparticles that the self-aggregation causes an unchanged or enhanced fluorescence can reduce the interference from non-target substance significantly.
引用
收藏
页码：1842 / 1846
页数：5
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