Brain-mapping projects using the common marmoset

被引:65
作者
Okano, Hideyuki [1 ,2 ]
Mitra, Partha [3 ]
机构
[1] RIKEN, Brain Sci Inst, Lab Marmoset Neural Architecture, Wako, Saitama 3510198, Japan
[2] Keio Univ, Sch Med, Dept Physiol, Shinjuku Ku, Tokyo 1608582, Japan
[3] Cold Spring Harbor Lab, New York, NY 11724 USA
关键词
Brain Mapping by Integrated; Neurotechnologies for Disease Studies (Brain/MINDS); Diffusion tensor imaging (DTI); Brain-wide connectivity maps; Macroscopic structural mapping; Mesoscopic structural mapping; Microscopic structural mapping; SPINAL-CORD; ATLAS; TRACTOGRAPHY; PRINCIPLES; CIRCUIT; ANATOMY; PATHWAY; FMRI;
D O I
10.1016/j.neures.2014.08.014
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset (Callithrix jacchus) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models. (C) 2014 The Authors. Published by Elsevier Ireland Ltd.
引用
收藏
页码:3 / 7
页数:5
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