New bibenzyl glycosides from leaves of Camellia oleifera Abel. with cytotoxic activities

被引：18
|
作者：
Chen, Yuelong [1 ]
Tang, Ling [1 ]
Feng, Baomin [1 ,2 ]
Shi, Liying [1 ]
Wang, Huiguo [1 ]
Wang, Yongqi [1 ]
机构：
[1] Dalian Univ, Coll Bioengn, Dalian 116622, Peoples R China
[2] Dalian Univ, Liaoning Key Lab Bioorgan Chem, Dalian 116622, Peoples R China
来源：
FITOTERAPIA | 2011年 / 82卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Camellia oleifera Abel; Theaceae; Bibenzyl glycosides; Cytotoxic activities; RESVERATROL; TRIGLYCOSIDES; SEEDS;
D O I：
10.1016/j.fitote.2010.12.009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Studies on the chemical constituents of leaves of Camellia oleifera Abel. led to the isolation of 3 new bibenzyl glycosides. Their structures have been elucidated as 1-(3',5'-dihydroxy)phenyl-2-(4 ''-O-beta-D-glucopyranosyl)phenylethane (1), 1-(3',5'-dimethoxy)phenyl-2-(4 ''-O-beta-D-glucopyranosyl)phenylethane (2) and 1-(3',5'-dimethoxy)phenyl-2-[4 ''-O-beta-D-glucopyranosyl (6 -> 1)-O-alpha-L-rhamnopyranosyl]phenylethane (3) through spectral studies including HR-ESI-MS, H-1 NMR, C-13 NMR and 2D NMR experiments. All the above 3 bibenzyl glycosides showed cytotoxic activities to Hela and hep2 cell lines. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：481 / 484
页数：4
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