Creating Biomaterials Inspired by the Microstructure of Cuttlebone

被引:5
作者
Cadman, Joseph [1 ]
Chen, Yuhang [1 ]
Zhou, Shiwei [1 ]
Li, Qing [1 ]
机构
[1] Univ Sydney, Sch AMME, Sydney, NSW 2006, Australia
来源
PRICM 7, PTS 1-3 | 2010年 / 654-656卷
关键词
Biomaterial; Graded material; Cuttlebone; Homogenisation; Scanning electron microscopy (SEM); Finite element analysis (FEA); Stereolithographic apparatus (SLA); DESIGN;
D O I
10.4028/www.scientific.net/MSF.654-656.2229
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The microstructure of cuttlebone is investigated using Scanning Electron Microscopy (SEM). A graded aspect ratio of the base cells between layers is evident in some samples. A method for designing graded biomaterials mimicking this cuttlebone microstructure is developed. Simplified 3D biomaterial samples are created using CAD software. These biomaterials are fabricated using a stereolithographic apparatus (SLA). The homogenisation technique is used to evaluate the mechanical properties of the original cuttlebone sample and the fabricated biomaterial sample. Good agreement is found between the Young's moduli of corresponding layers. However, it is inconclusive whether the Young's moduli have a proportional relationship to the aspect ratio of the base cell at this stage of the study.
引用
收藏
页码:2229 / 2232
页数:4
相关论文
共 9 条
[1]  
[Anonymous], 1978, ASYMPTOTIC ANAL PERI
[2]   GENERATING OPTIMAL TOPOLOGIES IN STRUCTURAL DESIGN USING A HOMOGENIZATION METHOD [J].
BENDSOE, MP ;
KIKUCHI, N .
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 1988, 71 (02) :197-224
[3]   Characterization of cuttlebone for a biomimetic design of cellular structures [J].
Cadman, Joseph ;
Zhou, Shiwei ;
Chen, Yuhang ;
Li, Wei ;
Appleyard, Richard ;
Li, Qing .
ACTA MECHANICA SINICA, 2010, 26 (01) :27-35
[4]  
Gower David, 1996, Biomimetics, V4, P37
[5]   Porous scaffold design for tissue engineering [J].
Hollister, SJ .
NATURE MATERIALS, 2005, 4 (07) :518-524
[6]   Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems [J].
Hutmacher, DW ;
Sittinger, M ;
Risbud, MV .
TRENDS IN BIOTECHNOLOGY, 2004, 22 (07) :354-362
[7]   Development of an indirect solid freeform fabrication process based on microstereolithography for 3D porous scaffolds [J].
Kang, Hyun-Wook ;
Seol, Young-Joon ;
Cho, Dong-Woo .
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2009, 19 (01)
[8]   Development of nano- and microscale composite 3D scaffolds using PPF/DEF-HA and micro-stereolithography [J].
Lee, Jin Woo ;
Ahn, GeunSeon ;
Kim, Dae Shick ;
Cho, Dong-Woo .
MICROELECTRONIC ENGINEERING, 2009, 86 (4-6) :1465-1467
[9]   Design of graded two-phase microstructures for tailored elasticity gradients [J].
Zhou, Shiwei ;
Li, Qing .
JOURNAL OF MATERIALS SCIENCE, 2008, 43 (15) :5157-5167