D-Dimer Level Predicts Angiographic No-Reflow Phenomenon After Percutaneous Coronary Intervention Within 2-7 Days of Symptom Onset in Patients with ST-Segment Elevation Myocardial Infarction

被引：12

作者：

Gong, Xue ^{[1
,2
]}

Lei, Xiaoting ^{[3
]}

Huang, Zheyong ^{[2
]}

Song, Yanan ^{[2
]}

Wang, Qibing ^{[2
]}

Qian, Juying ^{[2
]}

Ge, Junbo ^{[2
]}

机构：

[1] DeltaHlth Hosp, Dept Cardiol, Shanghai, Peoples R China

[2] Fudan Univ, Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Dept Cardiol, 180 Fenglin Rd, Shanghai 200032, Peoples R China

[3] 1 Hosp Tianshui City, Dept Cardiol, Tianshui, Gansu, Peoples R China

来源：

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH | 2021年 / 14卷 / 04期

基金：

中国国家自然科学基金;

关键词：

D-dimer; No-reflow; ST-segment elevation myocardial infarction; Primary percutaneous coronary intervention; PLASMA D-DIMER; VENOUS THROMBOEMBOLISM; DISTAL EMBOLIZATION; ANTICOAGULANT-THERAPY; PULMONARY-EMBOLISM; TRIAL; REPERFUSION; OCCLUSION; ANGIOPLASTY; BIOMARKERS;

D O I：

10.1007/s12265-020-09991-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It remains uncertain whether plasma D-dimer level can predict no-reflow in patients with STEMI who had pPCI after 48 h of symptom onset. This study retrospectively enrolled 229 consecutive patients who had pPCI for acute STEMI within 2-7 days of symptom onset between January 2008 and December 2018. Patients were divided into no-reflow group (TIMI flow grade 0-2) and reflow group (TIMI flow grade 3). Predictors of no-reflow were assessed by univariate and multivariate binary logistic regression analyses. Plasma D-dimer level can independently predict no-reflow in patients with STEMI who had pPCI within 2-7 days of symptom onset (OR 2.52 per 1 mg/L increase, 95% CI 1.16-5.47, p = 0.019). This finding indicated that pPCI may be safe and feasible for STEMI patients within 2-7 days of symptom onset with low D-dimer level.

引用

页码：728 / 734

页数：7

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