Laminitic Pain: Parallels with Pain States in Humans and Other Species

被引:19
作者
Collins, Simon N. [1 ,2 ]
Pollitt, Christopher [1 ]
Wylie, Claire E. [4 ]
Matiasek, Kaspar [3 ,5 ]
机构
[1] Univ Queensland, Sch Vet Sci, Gatton, Qld 4343, Australia
[2] Anim Hlth Trust, Ctr Equine Studies, Orthopaed Res Grp, Newmarket, Suffolk, England
[3] Anim Hlth Trust, Neuromuscular Res Grp, Newmarket, Suffolk, England
[4] Anim Hlth Trust, Epidemiol Res Grp, Ctr Prevent Med, Newmarket, Suffolk, England
[5] Anim Hlth Trust, Neuropathol Lab, Newmarket, Suffolk, England
关键词
Lamina's; Neuropathic pain; Inflammatory pain; Nociception; Dorsal root ganglia; SYMPATHETIC-NERVOUS-SYSTEM; HOOF WALL RESECTION; EQUINE LAMINITIS; NEUROPATHIC PAIN; INTRAOSSEOUS HYPERTENSION; CAPRINE TIBIA; SENSORY NEURONS; MECHANISMS; HORSES; EXPRESSION;
D O I
10.1016/j.cveq.2010.08.001
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Laminitis poses a threat to all horses and is widely considered as being one of the most important diseases of horses and a global equine welfare problem The effects of laminitis lead to debilitation development of pronounced digital pain and great suffering in the afflicted animal The precise pathophysiological processes that result in laminitic pain are poorly defined and hence the delivery of effective palliative care is clinically challenging Knowledge and understanding of pain states in other animal species may further aid the elucidation of equine laminitic pain mechanisms guide the search for treatable causes of this multifactorial problem and thereby help achieve enhanced therapeutic and palliative care However parallels drawn from pain states in other animals must consider species differences in both anatomy and physiology and the specific nature of the laminitic disease process.
引用
收藏
页码:643 / +
页数:31
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