Ribonucleotides in DNA: hidden in plain sight

被引：25

作者：

Jinks-Robertson, Sue ^{[1
]}

klein, Hannah L. ^{[2
]}

机构：

[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27708 USA

[2] NYU, Sch Med, Dept Biochem & Mol Pharmacol, New York, NY USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2015年 / 22卷 / 03期

关键词：

POLYMERASE-EPSILON; CATALYTIC DOMAINS; MISMATCH REPAIR; REPLICATION; MUTATIONS; REMOVAL; SIGNALS; ERRORS; H2;

D O I：

10.1038/nsmb.2981

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mapping of ribonucleotides to single-nucleotide resolution in yeast genomes provides new insight into the enzymology of DNA replication.

引用

页码：176 / 178

页数：3

共 26 条

[1] Ribonuclease H: the enzymes in eukaryotes [J].

Cerritelli, Susana M. ;

Crouch, Robert J. .

FEBS JOURNAL, 2009, 276 (06) :1494-1505

[2] Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation [J].

Clausen, Anders R. ;

Lujan, Scott A. ;

Burkholder, Adam B. ;

Orebaugh, Clinton D. ;

Williams, Jessica S. ;

Clausen, Maryam F. ;

Malc, Ewa P. ;

Mieczkowski, Piotr A. ;

Fargo, David C. ;

Smith, Duncan J. ;

Kunkel, Thomas A. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2015, 22 (03) :185-191

[3] Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection [J].

Crow, Yanick J. ;

Leitch, Andrea ;

Hayward, Bruce E. ;

Garner, Anna ;

Parmar, Rekha ;

Griffith, Elen ;

Ali, Manir ;

Semple, Colin ;

Aicardi, Jean ;

Babul-Hirji, Riyana ;

Baumann, Clarisse ;

Baxter, Peter ;

Bertini, Enrico ;

Chandler, Kate E. ;

Chitayat, David ;

Cau, Daniel ;

Dery, Catherine ;

Fazzi, Elisa ;

Goizet, Cyril ;

King, Mary D. ;

Klepper, Joerg ;

Lacombe, Didier ;

Lanzi, Giovanni ;

Lyall, Hermione ;

Martinez-Frias, Maria Luisa ;

Mathieu, Michele ;

McKeown, Carole ;

Monier, Anne ;

Oade, Yvette ;

Quarrell, Oliver W. ;

Rittey, Christopher D. ;

Rogers, R. Curtis ;

Sanchis, Amparo ;

Stephenson, John B. P. ;

Tacke, Uta ;

Till, Marianne ;

Tolmie, John L. ;

Tomlin, Pam ;

Voit, Thomas ;

Weschke, Bernhard ;

Woods, C. Geoffrey ;

Lebon, Pierre ;

Bonthron, David T. ;

Ponting, Chris P. ;

Jackson, Andrew P. .

NATURE GENETICS, 2006, 38 (08) :910-916

[4] A global profile of replicative polymerase usage [J].

Daigaku, Yasukazu ;

Keszthelyi, Andrea ;

Mueller, Carolin A. ;

Miyabe, Izumi ;

Brooks, Tony ;

Retkute, Renata ;

Hubank, Mike ;

Nieduszynski, Conrad A. ;

Carr, Antony M. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2015, 22 (03) :192-198

[5] Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control [J].

Feng, WY ;

D'Urso, G .

MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (14) :4495-4504

[6] Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair [J].

Ghodgaonkar, Medini Manohar ;

Lazzaro, Federico ;

Olivera-Pimentel, Maite ;

Artola-Boran, Mariela ;

Cejka, Petr ;

Reijns, Martin A. ;

Jackson, Andrew P. ;

Plevani, Paolo ;

Muzi-Falconi, Marco ;

Jiricny, Josef .

MOLECULAR CELL, 2013, 50 (03) :323-332

[7] Defective removal of ribonucleotides from DNA promotes systemic autoimmunity [J].

Guenther, Claudia ;

Kind, Barbara ;

Reijns, Martin A. M. ;

Berndt, Nicole ;

Martinez-Bueno, Manuel ;

Wolf, Christine ;

Tuengler, Victoria ;

Chara, Osvaldo ;

Lee, Young Ae ;

Huebner, Norbert ;

Bicknell, Louise ;

Blum, Sophia ;

Krug, Claudia ;

Schmidt, Franziska ;

Kretschmer, Stefanie ;

Koss, Sarah ;

Astell, Katy R. ;

Ramantani, Georgia ;

Bauerfeind, Anja ;

Morris, David L. ;

Graham, Deborah S. Cunninghame ;

Bubeck, Doryen ;

Leitch, Andrea ;

Ralston, Stuart H. ;

Blackburn, Elizabeth A. ;

Gahr, Manfred ;

Witte, Torsten ;

Vyse, Timothy J. ;

Melchers, Inga ;

Mangold, Elisabeth ;

Noethen, Markus M. ;

Aringer, Martin ;

Kuhn, Annegret ;

Luethke, Kirsten ;

Unger, Leonore ;

Bley, Annette ;

Lorenzi, Alice ;

Isaacs, John D. ;

Alexopoulou, Dimitra ;

Conrad, Karsten ;

Dahl, Andreas ;

Roers, Axel ;

Alarcon-Riquelme, Marta E. ;

Jackson, Andrew P. ;

Lee-Kirsch, Min Ae .

JOURNAL OF CLINICAL INVESTIGATION, 2015, 125 (01) :413-424

[8] Chromatin modifications and DNA repair: beyond double-strand breaks [J].

House, Nealia C. M. ;

Koch, Melissa R. ;

Freudenreich, Catherine H. .

FRONTIERS IN GENETICS, 2014, 5

[9] Choosing the right sugar: How polymerases select a nucleotide substrate [J].

Joyce, CM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (05) :1619-1622

[10] DNA polymerase ε catalytic domains are dispensable for DNA replication, DNA repair, and cell viability [J].

Kesti, T ;

Flick, K ;

Keränen, S ;

Syväoja, JE ;

Wittenberg, C .

MOLECULAR CELL, 1999, 3 (05) :679-685

← 1 2 3 →