Synthesis and NMR study of 6-aryl-3-(D-gluco-pentitol-1-yl)-7H-1,2,4-triazolo[3,4-b [1,3,4]thiadiazines

被引：0

作者：

Zhang, AJ ^{[1
]}

Zhang, LX

Xiong, Y

Xu, DJ

Li, XJ

机构：

[1] Sichuan Univ, Dept Chem, Chengdu 610064, Peoples R China

[2] Wenzhou Normal Coll, Inst Pharm, Wenzhou 325027, Peoples R China

[3] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 23卷 / 05期

关键词：

1,2,4-txiazolo[3,4-b][1,3,4]thiadiazine; synthesis; NMR;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Seven 6-aryl-3-(D-gluco-pentitol-1-yl)-7H-,1,2.,4-triazolo[3,4-b][1,3,4]thiadiazines were synthesized in high yields by the reaction of 4-amino-5-merrapto-3-( D-gluco-pentitol-1-yl)-1, 2, 4-triazole with substituted omega-bromoacetophenones. Their structures were confirmed by elemental analysis, IR, NMR and MS spectra. The NMR characteristics of the title compounds were further elucidated with 1D and 2D NMR techniques.

引用

页码：456 / 460

页数：5

共 8 条

[1] A novel approach for the synthesis of seco C-nucleoside analogues [J].

Awad, LF ;

El Ashry, EH .

NUCLEOSIDES & NUCLEOTIDES, 1999, 18 (4-5) :557-558

[2] Synthesis and antibacterial activity of s-triazoles, s-triazolo[3,4-b]-1,3,4-thiadiazines and s-triazolo[3,4-b]-1,3,4-thiadiazoles of 5-methylisoxazole [J].

Hui, XP ;

Zhang, LM ;

Zhang, ZY ;

Wang, Q ;

Wang, F .

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2000, 47 (03) :535-539

[3] Heterocyclic systems containing bridged nitrogen atom:: Synthesis and antibacterial activity of 3-(2-phenylquinolin-4-yl)/3-(1-p-chlorophenyl-5-methyl-1,2,3-triazol-4-yl)-s-triazolo[3,4-b]-1,3,4-thiadiazine derivatives [J].

Hui, XP ;

Dong, HS ;

Xu, PF ;

Zhang, ZY ;

Wang, Q ;

Gong, YN .

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2000, 47 (05) :1115-1119

[4] 1,2,4-triazoles. Improved synthesis of 5-substituted 4-amino-3-mercato-(4H)-1,2,4-triazoles and a facile route to 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles [J].

Invidiata, FP ;

Furno, G ;

Lampronti, I ;

Simoni, D .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1997, 34 (04) :1255-1258

[5]

Nizamuddin, 1999, J SCI IND RES INDIA, V58, P538

[6] SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-ARYLOXYALKYL-6-ARYL-7H-S-TRIAZOLO[3,4-B][1,3,4]THIADIAZINES [J].

PRASAD, AR ;

RAMALINGAM, T ;

RAO, AB ;

DIWAN, PV ;

SATTUR, PB .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1989, 24 (02) :199-201

[7]

Shi HJ, 1999, CHINESE J ORG CHEM, V19, P195

[8]

Sun X. H., 1999, HUAXUE TONGBAO, V62, P46

← 1 →