IGF-1 upregulates Survivin expression through PI-3K and CK2 pathways to inhibit 5-Fu induced apoptosis in esophageal carcinoma cells

被引:0
|
作者
Wong, Fen-Hwa
Juan, Hsien-Chia
Tsai, Hsin-Ting
Huang, Chi-Ying F.
机构
[1] Natl Yang Ming Univ, Fac Life Sci, Taipei, Taiwan
[2] Natl Yang Ming Univ, Inst Publ Hlth, Taipei, Taiwan
[3] Natl Hlth Res Inst, Div Canc, Taipei, Taiwan
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
790
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Participation of the PI-3K/Akt-NF-κB signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells
    Tong, Qiangsong
    Zheng, Liduan
    Lin, Li
    Li, Bo
    Wang, Danming
    Huang, Chuanshu
    Matuschak, George M.
    Li, Dechun
    RESPIRATORY RESEARCH, 2006, 7 (1)
  • [22] Six2 regulates the malignant progression and 5-FU resistance of hepatocellular carcinoma through the PI3K/AKT/mTOR pathway and DNMT1/E-cadherin methylation mechanism
    Li, Jianwang
    Cheng, Xiaozhen
    Huang, Denggao
    Cui, Ronghua
    NEOPLASMA, 2024, 71 (05) : 451 - 462
  • [23] HYDROTALCITE PROTECTS HUMAN ESOPHAGEAL KERATINOCYTE PROGENITOR CELLS FROM NSAID-INDUCED INJURY BY UPREGULATING EXPRESSION OF ANTI-APOPTOSIS PROTEIN SURVIVIN, IGF-1 AND COX2. DIRECT ACTIONS INDEPENDENT OF NEURAL AND VASCULAR FACTORS
    Tarnawski, Andrzej S.
    Ahluwalia, Amrita
    Gergely, Hella
    Jones, Michael K.
    GASTROENTEROLOGY, 2017, 152 (05) : S886 - S886
  • [24] Calycosin induces apoptosis in colorectal cancer cells, through modulating the ERβ/MiR-95 and IGF-1R, PI3K/Akt signaling pathways
    Zhao, Xinge
    Li, Xin
    Ren, Qianyao
    Tian, Jing
    Chen, Jian
    GENE, 2016, 591 (01) : 123 - 128
  • [25] Thimerosal-Induced Apoptosis in Mouse C2C12 Myoblast Cells Occurs through Suppression of the PI3K/Akt/Survivin Pathway
    Li, Wen-Xue
    Chen, Si-Fan
    Chen, Li-Ping
    Yang, Guang-Yu
    Li, Jun-Tao
    Liu, Hua-Zhang
    Zhu, Wei
    PLOS ONE, 2012, 7 (11):
  • [26] Artesunate enhances TRAIL-induced apoptosis in human cervical carcinoma cells through inhibition of the NF-κB and PI3K/Akt signaling pathways
    Thanaketpaisarn, Oranuch
    Waiwut, Pornthip
    Sakurai, Hiroaki
    Saiki, Ikuo
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2011, 39 (01) : 279 - 285
  • [27] Kurarinone attenuates hydrogen peroxide-induced oxidative stress and apoptosis through activating the PI3K/Akt signaling by upregulating IGF1 expression in human ovarian granulosa cells
    Li, Weiwei
    Yin, Xiurong
    Yan, Yani
    Liu, Cong
    Li, Gang
    ENVIRONMENTAL TOXICOLOGY, 2023, 38 (01) : 28 - 38
  • [28] SDF-1α inhibits hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells through PI3K/Akt and ERK1/2 signaling pathways
    Qi Yin
    Peifeng Jin
    Xuebin Liu
    Hua Wei
    Xiaoming Lin
    Chuang Chi
    Yu Liu
    Chengchao Sun
    Yingjie Wei
    Molecular Biology Reports, 2011, 38 : 9 - 16
  • [29] SDF-1α inhibits hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells through PI3K/Akt and ERK1/2 signaling pathways
    Yin, Qi
    Jin, Peifeng
    Liu, Xuebin
    Wei, Hua
    Lin, Xiaoming
    Chi, Chuang
    Liu, Yu
    Sun, Chengchao
    Wei, Yingjie
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (01) : 9 - 16
  • [30] IGF-1 induces myostatin expression through differential activation of the signaling pathways PI3K/Akt, Calcineurin/NFAT, ERK/CREB, CamK-MEF, Smad2/3 during myoblast proliferation and differentiation
    Flores, S.
    Zuloaga, R.
    Retamales, A.
    Andrade, C.
    Pino, K.
    Molina, A.
    Valdes, J. A.
    NEUROMUSCULAR DISORDERS, 2011, 21 (9-10) : 747 - 747