Biocompatible Blends Based on Polyvinyl Chloride and Natural Polymers for Medical Device Fabrication

New polymeric blends were prepared by mixing some receipts of polyvinyl chloride (PVC) for medical use with natural polymers (hydrolyzed collagen and a hydrolyzed collagen/elastin mixture), without the use of intercoupling agents. The mixtures were processed through rolling-pressing and extrusion. The new materials have physical and mechanical properties that allow their processing by using classical methods, specific for synthetic polymers. In vitro biocompatibility studies were performed on a primary culture of human dermal fibroblasts by the MTT test. The biocompatibility of the materials was tested in vitro by determining cell viability in a culture of human dermal fibroblasts by using the MTT method. The physical and mechanical properties and also the biocompatibility properties of the new materials recommend them to be used in the manufacture of medical devices.