Recent Progress in Intelligent Wearable Sensors for Health Monitoring and Wound Healing Based on Biofluids

被引:35
作者
Cheng, Siyang [1 ]
Gu, Zhen [1 ]
Zhou, Liping [1 ]
Hao, Mingda [1 ]
An, Heng [1 ]
Song, Kaiyu [1 ]
Wu, Xiaochao [2 ]
Zhang, Kexin [1 ]
Zhao, Zeya [1 ]
Dong, Yaozhong [3 ]
Wen, Yongqiang [1 ]
机构
[1] Univ Sci & Technol Beijing, Daxing Res Inst, Sch Chem & Biol Engn, Beijing Key Lab Bioengn & Sensing Technol, Beijing, Peoples R China
[2] Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou, Peoples R China
[3] Yantai Yuhuangding Hosp, Yantai, Peoples R China
基金
中国国家自然科学基金; 美国国家科学基金会;
关键词
intelligent; wearable; health monitoring; biofluids; targeted analytes; wound healing; EMBROIDERED ELECTROCHEMICAL SENSORS; INTERSTITIAL FLUID; URIC-ACID; SMART BANDAGE; CONTACT-LENS; WIRELESS CONNECTIVITY; LOW-COST; GLUCOSE; BIOSENSOR; SYSTEM;
D O I
10.3389/fbioe.2021.765987
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The intelligent wearable sensors promote the transformation of the health care from a traditional hospital-centered model to a personal portable device-centered model. There is an urgent need of real-time, multi-functional, and personalized monitoring of various biochemical target substances and signals based on the intelligent wearable sensors for health monitoring, especially wound healing. Under this background, this review article first reviews the outstanding progress in the development of intelligent, wearable sensors designed for continuous, real-time analysis, and monitoring of sweat, blood, interstitial fluid, tears, wound fluid, etc. Second, this paper reports the advanced status of intelligent wound monitoring sensors designed for wound diagnosis and treatment. The paper highlights some smart sensors to monitor target analytes in various wounds. Finally, this paper makes conservative recommendations regarding future development of intelligent wearable sensors.
引用
收藏
页数:21
相关论文
共 188 条
[41]   Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis [J].
Gao, Wei ;
Emaminejad, Sam ;
Nyein, Hnin Yin Yin ;
Challa, Samyuktha ;
Chen, Kevin ;
Peck, Austin ;
Fahad, Hossain M. ;
Ota, Hiroki ;
Shiraki, Hiroshi ;
Kiriya, Daisuke ;
Lien, Der-Hsien ;
Brooks, George A. ;
Davis, Ronald W. ;
Javey, Ali .
NATURE, 2016, 529 (7587) :509-+
[42]   A flexible multiplexed immunosensor for point-of-care in situ wound monitoring [J].
Gao, Yuji ;
Nguyen, Dat T. ;
Yeo, Trifanny ;
Lim, Su Bin ;
Tan, Wei Xian ;
Madden, Leigh Edward ;
Jin, Lin ;
Long, Ji Yong Kenan ;
Aloweni, Fazila Abu Bakar ;
Liew, Yi Jia Angela ;
Tan, Mandy Li Ling ;
Ang, Shin Yuh ;
Maniya, Sivagame D. O. ;
Abdelwahab, Ibrahim ;
Loh, Kian Ping ;
Chen, Chia-Hung ;
Becker, David Laurence ;
Leavesley, David ;
Ho, John S. ;
Lim, Chwee Teck .
SCIENCE ADVANCES, 2021, 7 (21)
[43]   A redox-responsive hyaluronic acid-based hydrogel for chronic wound management [J].
Gao, Ziyu ;
Gotland, Ben ;
Tronci, Giuseppe ;
Thornton, Paul D. .
JOURNAL OF MATERIALS CHEMISTRY B, 2019, 7 (47) :7494-7501
[44]   Muscle-Inspired Self-Healing Hydrogels for Strain and Temperature Sensor [J].
Ge, Gang ;
Lu, Yao ;
Qu, Xinyu ;
Zhao, Wen ;
Ren, Yanfang ;
Wang, Wenjun ;
Wang, Qian ;
Huang, Wei ;
Dong, Xiaochen .
ACS NANO, 2020, 14 (01) :218-228
[45]   Flexible Breathable Nanomesh Electronic Devices for On-Demand Therapy [J].
Gong, Min ;
Wan, Pengbo ;
Ma, Di ;
Zhong, Mengjuan ;
Liao, Meihong ;
Ye, Jingjing ;
Shi, Rui ;
Zhang, Liqun .
ADVANCED FUNCTIONAL MATERIALS, 2019, 29 (26)
[46]   Tumor interstitial fluid - A treasure trove of cancer biomarkers [J].
Gromov, Pavel ;
Gromova, Irina ;
Olsen, Charlotta J. ;
Timmermans-Wielenga, Vera ;
Talman, Mai-Lis ;
Serizawa, Reza R. ;
Moreira, Jose M. A. .
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2013, 1834 (11) :2259-2270
[47]   Bandage-Based Wearable Potentiometric Sensor for Monitoring Wound pH [J].
Guinovart, Tomas ;
Valdes-Ramirez, Gabriela ;
Windmiller, Joshua R. ;
Andrade, Francisco J. ;
Wang, Joseph .
ELECTROANALYSIS, 2014, 26 (06) :1345-1353
[48]   Factors Affecting Wound Healing [J].
Guo, S. ;
DiPietro, L. A. .
JOURNAL OF DENTAL RESEARCH, 2010, 89 (03) :219-229
[49]   Low melting point metal-based flexible 3D biomedical microelectrode array by phase transition method [J].
Guo, Shengxin ;
Lin, Rongzan ;
Wang, Lei ;
Lau, Shinying ;
Wang, Qian ;
Liu, Ran .
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 99 :735-739
[50]   Wound repair and regeneration [J].
Gurtner, Geoffrey C. ;
Werner, Sabine ;
Barrandon, Yann ;
Longaker, Michael T. .
NATURE, 2008, 453 (7193) :314-321