The photodegradation of a zinc phthalocyanine

被引:16
作者
Gumustas, M. K. [2 ]
Sesalan, B. S. [1 ]
Atukeren, P. [2 ]
Yavuz, B. [2 ]
Gul, A. [1 ]
机构
[1] Tech Univ Istanbul, Dept Chem, TR-34469 Istanbul, Turkey
[2] Istanbul Univ, Dept Biochem, TR-34093 Istanbul, Turkey
关键词
Phthalocyanine; Dye; Cationic; Mice; Photobleaching; ALUMINUM PHTHALOCYANINE; INFARCT SIZE; LOCALIZATION; DERIVATIVES; REDUCTION; THERAPY;
D O I
10.1080/00958972.2010.534987
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A water-soluble zinc phthalocyanine (Pc), ZnPc (3), bearing 12 dimethylamino groups, which enhance the solubility of the macrocycle was synthesized and characterized. Photobleaching of the compound was examined both invivo and invitro. Laser irradiation causes photo-oxidation of the newly synthesized ZnPc. A photobleachable phthalocyanine can be an alternative in imaging; phthalocyanine dyes are used in imaging the cardiovascular system. Besides, it can be used in fluorescein angiography in some cases. When compared to stable ones, a photobleaching ZnPc (3) might be an attractive compound for imaging in medicine.
引用
收藏
页码:4319 / 4331
页数:13
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