Evidences of a New Psychobiotic Formulation on Body Composition and Anxiety

被引：46

作者：

Colica, Carmela ^{[1
]}

Avolio, Ennio ^{[2
]}

Bollero, Patrizio ^{[3
]}

de Miranda, Renata Costa ^{[4
,5
]}

Ferraro, Simona ^{[6
]}

Salimei, Paola Sinibaldi ^{[7
]}

De Lorenzo, Antonino ^{[7
]}

Di Renzo, Laura ^{[7
]}

机构：

[1] Magna Graecia Univ Catanzaro, CNR, IBFM UOS Germaneto, Campus Salvatore Venuta, I-88100 Catanzaro, Italy

[2] Univ Calabria, Comparat Neuroanat Lab Ecol Dept, I-87030 Cosenza, Italy

[3] Univ Roma Tor Vergata, Dept Syst Med, Via Montpellier 1, I-00133 Rome, Italy

[4] Univ Roma Tor Vergata, PhD Sch Med Surg Appl Sci, Via Montpellier 1, I-00133 Rome, Italy

[5] Minist Educ Brazil, CAPES Fdn, CAPES Scholarship Proc BEX 13264 13 3, BR-70040020 Brasilia, DF, Brazil

[6] Hlth Ctr Srl, Biomed & Nutr Ctr, I-87100 Cosenza, Italy

[7] Univ Roma Tor Vergata, Sect Clin Nutr & Nutrigen, Dept Biomed & Prevent, Via Montpellier 1, I-00133 Rome, Italy

来源：

MEDIATORS OF INFLAMMATION | 2017年 / 2017卷

关键词：

PROMOTER GENE POLYMORPHISM; GUT MICROBIOTA; INSULIN-RESISTANCE; PHYSICAL-ACTIVITY; FAT MASS; OBESITY; ASSOCIATION; WEIGHT; OVERWEIGHT; IMPACT;

D O I：

10.1155/2017/5650627

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Background. Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods. Eligible patients were randomly divided into three groups: psychobiotics oral suspension group (POSG); dietary treatment group (DTG); combined treatment group (CTG). All subjects underwent body composition and psychological profile evaluation. Results. Significant changes in body composition parameters in each group were relieved after all treatments. Hamilton anxiety rating scale (HAM-A) highlighted a significant reduction of the total score for all study population after treatments in POSG (p = 0 01) and CTG (p = 0 04). A reduction of HAM-A total score in anxious subjects in POSG or CTG and a significant reduction of positive subjects for HAM-A in POSG (p = 0 03) and in CDG (p = 0 01) were shown. Discussion. Three-week intake of selected POS represents a good approach to solve problems related to obesity and behavior disorders. However, new clinical trials need to be performed on a larger population and for a longer period of treatment before definitive conclusions can be made. This trial is registered with NCT01890070.

引用

页数：10

共 64 条

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