Overview: Global and Local Impact of Antibiotic Resistance

被引：179

作者：

Watkins, Richard R. ^{[1
,2
]}

Bonomo, Robert A. ^{[3
,4
,5
,6
]}

机构：

[1] Cleveland Clin, Akron Gen Med Ctr, Div Infect Dis, 224 West Exchange St,Suite 290, Akron, OH 44302 USA

[2] North East Ohio Med Univ, Dept Internal Med, Rootstown, OH USA

[3] Dept Vet Affairs Med Ctr, Louis Stokes Cleveland, Med & Res Serv, 10701 East Blvd, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA

[5] Case Western Reserve Univ, Sch Med, Dept Pharmacol, Cleveland, OH 44106 USA

[6] Case Western Reserve Univ, Sch Med, Dept Mol Biol & Microbiol, Cleveland, OH 44106 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2016年 / 30卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Antibiotic resistance; Infections; Agriculture; Public health; ENTERICA SEROVAR TYPHI; ANTIMICROBIAL RESISTANCE; HUMAN HEALTH; DISSEMINATION; EPIDEMIOLOGY; MECHANISMS; CHALLENGES; DRUGS;

D O I：

10.1016/j.idc.2016.02.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The rapid and ongoing spread of antibiotic resistance poses a serious threat to global public health. The indiscriminant use of antibiotics in agriculture and human medicine along with increasingly connected societies has fueled the distribution of antibiotic-resistant bacteria. These factors together have led to rising numbers of infections caused by multidrug-resistant and pan-resistant bacteria, with increases in morbidity and mortality. This article summarizes the trends in antibiotic resistance, discusses the impact of antibiotic resistance on society, and reviews the use of antibiotics in agriculture. Feasible ways to tackle antibiotic resistance to avert a post-antibiotic era are suggested.

引用

页码：313 / +

页数：11

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