Antibacterial and antioxidant potential of GC-MS analysis of crude ethyl acetate extract from the tropical mangrove plant Avicennia officinalis L.

被引：31

作者：

Lalitha, P. ^{[1
]}

Parthiban, A. ^{[1
]}

Sachithanandam, V. ^{[1
]}

Purvaja, R. ^{[1
]}

Ramesh, R. ^{[1
]}

机构：

[1] Govt India, Minist Environm Forest & Climate Change, Natl Ctr Sustainable Coastal Management, Anna Univ Campus, Chennai 600025, Tamil Nadu, India

来源：

SOUTH AFRICAN JOURNAL OF BOTANY | 2021年 / 142卷

关键词：

Antibacterial activity; Antioxidant activity; A; officinalis; Mangrove plants; GC-MS analysis; SECONDARY METABOLITES;

D O I：

10.1016/j.sajb.2021.06.023

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Avicennia officinalis L. is an important mangrove plant used in traditional medicine to treat various diseases like asthma, dyspepsia, paralysis, tumor and rheumatism in aboriginal peoples in Andaman and Nicobar Islands (ANI). The study analyzed and separated bioactive speciation of ethyl acetate leaves extract of A. officinalis from tropical mangrove plants by Gas Chromatography-Mass Spectrometry (GCMS) and further antimicrobial and antioxidant potential assay. GC-MS results of A. officinalis identified eight different bioactive compounds namely Trans-cinnamic acid, 2,4-Di-tert-butyl phenol, Phenol, 3-(2phenylethyl, n-hexadecanoic acid, Dibutyl phthalate, Phytol, beta-Sitosterol, Androst-7-ene-6, 17-dione and 2,3,14-trihydroxy. The natural products present in A. officinalis showed strong antibacterial activity against different bacteria like gram-positive strain: Streptococcus mutans (19 mm maximum zone of inhibition), Bacillus subtilis (17 mm), Pseudomonas aeruginosa (16 mm), and gram-negative: Klebsiella pneumonia (22 mm) and Enterobacter aerohenes (14 mm). Further, this crude extract showed good antioxidant activity with IC50 values of 23.60 +/- 0.43 mu g/ml measured using the DPPH method. Thus, the study put forth the promising role of ethyl acetate leaves extract of A. officinalis in the formulation of therapeutic drugs against bacterial infections, antioxidants and cancer. (C) 2021 SAAB. Published by Elsevier B.V. All rights reserved.

引用

页码：149 / 155

页数：7

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