Wind tunnel tests were performed in low-turbulence uniform flow to measure the wind pressures on the surfaces of sixteen 2D prisms with various side ratios and chamfered corners. First, the effects of chamfered corners on wind pressure coefficients and pressure correlation coefficients on the side surfaces of models with various side ratios are analyzed. Second, the mean drag coefficients, root-mean-square (RMS) drag coefficients and RMS lift coefficients of the 16 models are discussed. Third, power spectra of aerodynamic force coefficients of the 16 models are analyzed, and the Strouhal numbers are obtained by analyzing the power spectra of lift coefficients. Finally, three typical points on the surfaces of each model are selected, and the power spectra of pressure coefficients for these points are discussed. Based on the above analysis, physical mechanisms of the effects of chamfered corners on the aerodynamic characteristics of 2D prisms with various side ratios are revealed.