Multi-Layered Hydrogels for Biomedical Applications

被引：52

作者：

Liu, Guiting ^{[1
]}

Ding, Zhangfan ^{[2
]}

Yuan, Qijuan ^{[1
]}

Xie, Huixu ^{[2
]}

Gu, Zhipeng ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Biomed Engn, Key Lab Sensing Technol & Biomed Instrument Guang, Guangzhou, Guangdong, Peoples R China

[2] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, State Key Lab Oral Dis,Dept Head & Neck Oncol, Chengdu, Sichuan, Peoples R China

来源：

FRONTIERS IN CHEMISTRY | 2018年 / 6卷

基金：

中国国家自然科学基金;

关键词：

multi-layered hydrogel; layer-by-layer self-assembly; step-wise; photo-polymerization; sequential electrospinning; biomedical application; PHOSPHOLIPID POLYMER HYDROGEL; BIOINSPIRED MATERIALS; MECHANICAL-PROPERTIES; CONTROLLED-RELEASE; DRUG-RELEASE; 3D; COATINGS; DELIVERY; FILMS; BIOMATERIALS;

D O I：

10.3389/fchem.2018.00439

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multi-layered hydrogels with organization of various functional layers have been the materials of choice for biomedical applications. This review summarized the recent progress of multi-layered hydrogels according to their preparation methods: layer-by-layer self-assembly technology, step-wise technique, photo-polymerization technique and sequential electrospinning technique. In addition, their morphology and biomedical applications were also introduced. At the end of this review, we discussed the current challenges to the development of multi-layered hydrogels and pointed out that 3D printing may provide a new platform for the design of multi-layered hydrogels and expand their applications in the biomedical field.

引用

页数：10

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