Products of aqueous vitamin B5 (pantothenic acid) formed by free radical reactions

被引：4

作者：

Schittl, H. ^{[1
]}

Quint, R. M. ^{[1
]}

Getoff, N. ^{[1
]}

机构：

[1] Univ Vienna, Dept Nutr Sci, Sect Radiat Biol, A-1090 Vienna, Austria

来源：

RADIATION PHYSICS AND CHEMISTRY | 2007年 / 76卷 / 10期

关键词：

vitamin B5; pantothenic acid; radiolysis of vitamin B5; products of vitamin B5;

D O I：

10.1016/j.radphyschem.2007.01.009

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The radiolysis of aqueous vitamin B5 (pantothenic acid) has been investigated under various experimental conditions. The highest vitamin degradation (G = 3.22) was observed in solutions saturated with N2O, where 90% OH radicals are operating. As final products, the following were established: aldehydes, carboxylic acids and ammonia. Their yield strongly depends on the presence/absence of air as well as on N2O (used to convert e (a) over barq into OH) and was determined as a function of absorbed radiation dose. HPLC-analysis showed that in all media, a main product is formed, having the highest yield in aerated solutions. Based on the chemical analysis, it appears that the OH radicals are most involved in the degradation process. A precise sequence of the reaction steps could not be given presently, because of the implication of many simultaneous reactions. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1594 / 1599

页数：6

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