Vaccine Delivery Methods into the Future

被引：23

作者：

Apostolopoulos, Vasso ^{[1
]}

机构：

[1] Victoria Univ, Coll Hlth & Biomed, Ctr Chron Dis, Melbourne, Vic 3021, Australia

来源：

VACCINES | 2016年 / 4卷 / 02期

关键词：

vaccine; vaccine delivery; antigen delivery; immunotherapy; DNA VACCINES; PEPTIDE; IMMUNOTHERAPY; RESPONSES; CARRIERS; DESIGN;

D O I：

10.3390/vaccines4020009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Several modes of vaccine delivery have been developed in the last 25 years, which induce strong immune responses in pre-clinical models and in human clinical trials. Some modes of delivery include, adjuvants (aluminum hydroxide, Ribi formulation, QS21), liposomes, nanoparticles, virus like particles, immunostimulatory complexes (ISCOMs), dendrimers, viral vectors, DNA delivery via gene gun, electroporation or Biojector 2000, cell penetrating peptides, dendritic cell receptor targeting, toll-like receptors, chemokine receptors and bacterial toxins. There is an enormous amount of information and vaccine delivery methods available for guiding vaccine and immunotherapeutics development against diseases.

引用

页数：5

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