The EANM guideline for radiosynoviorthesis

被引：24

作者：

Kampen, W. U. ^{[1
]}

Boddenberg-Paetzold, B. ^{[2
]}

Fischer, M. ^{[3
]}

Gabriel, M. ^{[4
,5
]}

Klett, R. ^{[6
]}

Konijnenberg, M. ^{[7
]}

Kresnik, E. ^{[8
]}

Lellouche, H. ^{[9
,10
]}

Paycha, F. ^{[11
]}

Terslev, L. ^{[12
]}

Turkmen, C. ^{[13
]}

van der Zant, F. ^{[14
]}

Antunovic, L. ^{[15
]}

Panagiotidis, E. ^{[16
]}

Gnanasegaran, G. ^{[17
]}

Kuwert, T. ^{[18
]}

Van den Wyngaert, T. ^{[19
,20
]}

机构：

[1] Radiol Allianz, Nukl Med Spitalerhof, Spitalerstr 8, D-20095 Hamburg, Germany

[2] Praxis NURAMED West, Max Planck Str 27a, D-50858 Cologne, Germany

[3] Praxis Radiol & Nukl Med, Friedrich Ebert Str 50, D-34117 Kassel, Germany

[4] Johannes Kepler Univ Linz, Kepler Univ Hosp Linz GmbH, Inst Nucl Med & Endocrinol, Med Fac, Altenberger Str 69, A-4040 Linz, Austria

[5] Krankenhausstr 9, A-4020 Linz, Austria

[6] Standort Giessen, Hanau Frankfurt Offenbach Giessen, UBAG Nukl Med, Paul Zipp Str 171-173, D-35398 Giessen, Germany

[7] Erasmus MC, Nucl Geneeskunde, Dr Molewaterpl 40, NL-3015 GD Rotterdam, Netherlands

[8] Privatklinik Villach, Inst Nukl Med, Dr Walter Hochsteinerstr 4, A-9504 Warmbad Villach, Austria

[9] Hop Lariboisiere, Ctr Viggo Petersen, Unite Rhumatol Affect La Main, 2 Rue Ambroise Pare, F-75010 Paris, France

[10] Inst Rhumatol Intervent, 13 Rue Thouin, F-75005 Paris, France

[11] Hop Lariboisiere, AP HP, Nucl Med Serv, 2 Rue Ambroise Pare, F-75010 Paris, France

[12] Copenhagen Univ Hosp, Ctr Rheumatol & Spine Dis, Rigshosp, Valdemar Hansens Vej 17, DK-2600 Glostrup, Denmark

[13] Istanbul Univ, Istanbul Med Fac, Dept Nucl Med, TR-34390 Istanbul, Turkey

[14] Noordwest Ziekenhuisgrp, Nucl Geneeskunde, Postbus 501, NL-1800 AM Alkmaar, Netherlands

[15] IRCCS Humanitas Res Hosp, Diagnost Imaging Dept, Via Manzoni 56, I-20089 Milan, Italy

[16] Oncol Ctr Theageneio, Dept Nucl Med, Al Symeonidis 2 Str, Thessaloniki 54007, Greece

[17] Royal Free London NHS Fdn Trust, Dept Nucl Med, London, England

[18] Friedrich Alexander Univ, Erlangen Nurnberg, Clin Nucl Med, Erlangen, Germany

[19] Antwerp Univ Hosp, Drie Eikenstr 655, B-2650 Edegem, Belgium

[20] Univ Antwerp, Mol Imaging Ctr Antwerp MICA IPPON, Fac Med & Hlth Sci, Antwerp, Belgium

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2022年 / 49卷 / 02期

关键词：

Synovitis; Arthritis; Radiosynoviorthesis; MODIFYING ANTIRHEUMATIC DRUGS; CHRONIC HEMOPHILIC SYNOVITIS; UPPER EXTREMITY JOINTS; LONG-TERM EVALUATION; NERVE GROWTH-FACTOR; RADIATION SYNOVECTOMY; RHEUMATOID-ARTHRITIS; RADIONUCLIDE SYNOVECTOMY; BIOLOGICAL DOSIMETRY; Y-90; SYNOVECTOMY;

D O I：

10.1007/s00259-021-05541-7

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose Radiosynoviorthesis (RSO) using the intraarticular application of beta-particle emitting radiocolloids has for decades been used for the local treatment of inflammatory joint diseases. The injected radiopharmaceuticals are phagocytized by the superficial macrophages of the synovial membrane, resulting in sclerosis and fibrosis of the formerly inflamed tissue, finally leading to reduced joint effusion and alleviation of joint pain. Methods The European Association of Nuclear Medicine (EANM) has written and approved these guidelines in tight collaboration with an international team of clinical experts, including rheumatologists. Besides clinical and procedural aspects, different national legislative issues, dosimetric considerations, possible complications, and side effects are addressed. Conclusion These guidelines will assist nuclear medicine physicians in performing radiosynoviorthesis. Since there are differences regarding the radiopharmaceuticals approved for RSO and the official indications between several European countries, this guideline can only give a framework that must be adopted individually.

引用

页码：681 / 708

页数：28

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