Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

被引：235
作者：
Zhao, Tianjiao [1 ,3 ,4 ]
Wu, Wei [2 ,4 ]
Sui, Lihua [3 ,5 ]
Huang, Qiong [1 ,4 ]
Nan, Yayun [6 ]
Liu, Jianhua [7 ]
Ai, Kelong [3 ,5 ]
机构：
[1] Cent South Univ, Xiangya Hosp, Dept Pharm, Changsha 410087, Peoples R China
[2] Cent South Univ, Xiangya Hosp, Dept Geriatr Surg, Changsha 410087, Peoples R China
[3] Cent South Univ, Xiangya Sch Pharmaceut Sci, Changsha 410008, Peoples R China
[4] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410087, Peoples R China
[5] Cent South Univ, Xiangya Sch Pharmaceut Sci, Hunan Prov Key Lab Cardiovasc Res, Changsha 410008, Peoples R China
[6] Ningxia Peoples Hosp, Geriatr Med Ctr, Yinchuan 750003, Ningxia, Peoples R China
[7] Second Hosp Jilin Univ, Dept Radiol, Changchun 130041, Peoples R China
来源：
BIOACTIVE MATERIALS | 2022年 / 7卷
基金：
中国国家自然科学基金;
关键词：
Reactive oxygen species; Myocardial ischemia reperfusion injury; Nano-enzyme; Nanocarrier; Antioxidant therapy; MESENCHYMAL STEM-CELLS; IRON-OXIDE NANOPARTICLES; ISCHEMIA/REPERFUSION INJURY; OXIDATIVE STRESS; NITRIC-OXIDE; ISCHAEMIA/REPERFUSION INJURY; MITOCHONDRIAL DYSFUNCTION; SUPEROXIDE-PRODUCTION; ACTIVE NANOMATERIALS; ANTIOXIDANT ACTIVITY;
D O I：
10.1016/j.bioactmat.2021.06.006
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high. Reperfusion injuries are inevitable due to the generation of reactive oxygen species (ROS) and apoptosis of cardiac muscle cells. However, many antioxidant and anti-inflammatory drugs are largely limited by pharmacokinetics and route of administration, such as short half-life, low stability, low bioavailability, and side effects for treatment myocardial ischemia reperfusion injury. Therefore, it is necessary to develop effective drugs and technologies to address this issue. Fortunately, nanotherapies have demonstrated great opportunities for treating myocardial ischemia reperfusion injury. Compared with traditional drugs, nanodrugs can effectively increase the therapeutic effect and reduces side effects by improving pharmacokinetic and pharmacodynamic properties due to nanodrugs' size, shape, and material characteristics. In this review, the biology of ROS and molecular mechanisms of myocardial ischemia reperfusion injury are discussed. Furthermore, we summarized the applications of ROS-based nanoparticles, highlighting the latest achievements of nanotechnology researches for the treatment of myocardial ischemia reperfusion injury.
引用
收藏
页码：47 / 72
页数：26
相关论文
共 273 条
[61]   Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis [J].
Foerstermann, Ulrich ;
Xia, Ning ;
Li, Huige .
CIRCULATION RESEARCH, 2017, 120 (04) :713-735
[62]   Reactive Oxygen Species in Metabolic and Inflammatory Signaling [J].
Forrester, Steven J. ;
Kikuchi, Daniel S. ;
Hernandes, Marina S. ;
Xu, Qian ;
Griendling, Kathy K. .
CIRCULATION RESEARCH, 2018, 122 (06) :877-+
[63]   MACROPHAGES AND CARDIOVASCULAR HEALTH [J].
Frodermann, Vanessa ;
Nahrendorf, Matthias .
PHYSIOLOGICAL REVIEWS, 2018, 98 (04) :2523-2569
[64]   Gene delivery to the myocardium by intrapericardial injection [J].
Fromes, Y ;
Salmon, A ;
Wang, X ;
Collin, H ;
Rouche, A ;
Hagège, A ;
Schwartz, K ;
Fiszman, MY .
GENE THERAPY, 1999, 6 (04) :683-688
[65]   Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice [J].
Fujiwara, Masaki ;
Matoba, Tetsuya ;
Koga, Jun-Ichiro ;
Okahara, Arihide ;
Funamoto, Daiki ;
Nakano, Kaku ;
Tsutsui, Hiroyuki ;
Egashira, Kensuke .
CARDIOVASCULAR RESEARCH, 2019, 115 (07) :1244-1255
[66]   Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis [J].
Fukai, Tohru ;
Ushio-Fukai, Masuko .
CELLS, 2020, 9 (08)
[67]   Neuroprotection against cerebral ischemia/reperfusion injury by intravenous administration of liposomal fasudil [J].
Fukuta, Tatsuya ;
Asai, Tomohiro ;
Sato, Akihiko ;
Namba, Mio ;
Yanagida, Yosuke ;
Kikuchi, Takashi ;
Koide, Hiroyuki ;
Shimizu, Kosuke ;
Oku, Naoto .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2016, 506 (1-2) :129-137
[68]   Intrinsic peroxidase-like activity of ferromagnetic nanoparticles [J].
Gao, Lizeng ;
Zhuang, Jie ;
Nie, Leng ;
Zhang, Jinbin ;
Zhang, Yu ;
Gu, Ning ;
Wang, Taihong ;
Feng, Jing ;
Yang, Dongling ;
Perrett, Sarah ;
Yan, Xiyun .
NATURE NANOTECHNOLOGY, 2007, 2 (09) :577-583
[69]   Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis [J].
Garikipati, Venkata Naga Srikanth ;
Verma, Suresh Kumar ;
Cheng, Zhongjian ;
Liang, Dongming ;
Truongcao, May M. ;
Cimini, Maria ;
Yue, Yujia ;
Huang, Grace ;
Wang, Chunlin ;
Benedict, Cindy ;
Tang, Yan ;
Mallaredy, Vandana ;
Ibetti, Jessica ;
Grisanti, Laurel ;
Schumacher, Sarah M. ;
Gao, Erhe ;
Rajan, Sudarsan ;
Wilusz, Jeremy E. ;
Goukassian, David ;
Houser, Steven R. ;
Koch, Walter J. ;
Kishore, Raj .
NATURE COMMUNICATIONS, 2019, 10 (1)
[70]   Regulation of microRNA function in animals [J].
Gebert, Luca F. R. ;
MacRae, Ian J. .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2019, 20 (01) :21-37
234567891011