In a theoretical model of self-regulated learning, cognitive and motivational components are important for academic success (Boekaerts, 1996). It was hypothesized that both, cognitive components (the use of learning strategies) and motivational components (goal-orientation and self-efficacy), predict academic success. Academic success was indexed by academic satisfaction and by academic achievement. Data analyses were based on a sample of N = 77 university students studying medicine. Learning strategies as well as motivational variables turned out to be significant predictors of academic satisfaction. For academic achievement, in contrast, the combination of self-regulatory skills and deep-processing learning predicted exam performance, but not goal orientation and self-efficacy.