Enantioselective intramolecular Rauhut-Currier reaction catalyzed by chiral phosphinothiourea

被引：71

作者：

Gong, Jing-Jing ^{[1
,2
]}

Li, Tian-Ze ^{[1
,2
]}

Pan, Kun ^{[1
,2
]}

Wu, Xin-Yan ^{[1
,2
,3
]}

机构：

[1] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

[3] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 05期

基金：

中国国家自然科学基金;

关键词：

MORITA-BAYLIS-HILLMAN; AMINO-ACID; PHOSPHINES; CYSTEINE;

D O I：

10.1039/c0cc04412a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral organophosphine-catalyzed enantioselective Rauhut-Currier reaction has been disclosed for the first time. With L-valine-derived phosphinothiourea, the intramolecular Rauhut-Currier reaction of bis(enones) was achieved in good yields (up to 99%) with excellent enantioselectivities (up to 99.4% ee).

引用

页码：1491 / 1493

页数：3

共 19 条

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