Ni-Catalyzed Reductive Allylation of Unactivated Alkyl Halides with Allylic Carbonates

被引：101

作者：

Dai, Yijing ^{[1
]}

Wu, Fan ^{[1
]}

Zang, Zhenhua ^{[1
]}

You, Hengzhi ^{[1
]}

Gong, Hegui ^{[1
]}

机构：

[1] Shanghai Univ, Dept Chem, Shanghai 200444, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 03期

关键词：

alkyl halides; allylation; allylic compounds; nickel; reductive coupling; CROSS-COUPLING REACTIONS; BOND FORMATION; ARYL HALIDES; C-C; NICKEL; COPPER; CHLORIDES; REAGENTS; ALCOHOLS; BROMIDES;

D O I：

10.1002/chem.201102984

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Game of two electrophiles: Two partially positively charged sp 3 carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：808 / 812

页数：5

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