Magnesiation of functionalized iodobenzenes at room temperature: clarification of the stability of ethoxycarbonylphenylmagnesium iodides

被引：6

作者：

Sugimoto, O ^{[1
]}

Aoki, K ^{[1
]}

Tanji, K ^{[1
]}

机构：

[1] Univ Shizuoka, Sch Food & Nutr Sci, Organ Chem Lab, Shizuoka, Japan

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 09期

关键词：

magnesiation; Grignard reagent; active magnesium;

D O I：

10.1016/j.tetlet.2003.12.136

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Magnesiation of functionalized aromatic halide, ethyl 3- or 4-iodobenzoate, was accomplished using active magnesium. The resulting phenylmagnesium iodides decomposed little by little in proportion to extension of the reaction time at room temperature. The magnesiation followed by addition of carbonyl compounds gave the corresponding adducts in good to moderate yields. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1915 / 1917

页数：3

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