Asperaculin A, a Sesquiterpenoid from a Marine-Derived Fungus, Aspergillus aculeatus

被引:41
作者
Ingavat, Nattha [1 ,2 ,3 ]
Mahidol, Chulabhorn [1 ,2 ,3 ,4 ]
Ruchirawat, Somsak [1 ,2 ,3 ,4 ]
Kittakoop, Prasat [1 ,2 ,3 ]
机构
[1] Chulabhorn Grad Inst, Bangkok 10210, Thailand
[2] Ctr Environm Hlth Toxicol & Management Chem ETM, Chem Biol Program, Bangkok 10210, Thailand
[3] Chulabhorn Res Inst, Bangkok 10210, Thailand
[4] Mahidol Univ, Chulabhorn Res Ctr, Inst Mol Biosci, Bangkok 10400, Thailand
来源
JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 07期
关键词
NATURAL-PRODUCTS; PENICILLIUM-GRISEOFULVUM; FUNGICOLOUS ISOLATE; DRUG DISCOVERY; METABOLITE;
D O I
10.1021/np200221w
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A novel sesquiterpenoid, asperaculin A (1), possessing a novel [5,5,5,6]fenestrane ring system, was isolated from the marine-derived fungus Aspergillus aculeatus CRI323-04. The structure of asperaculin A (1) was established by analysis of spectroscopic data. The name aspergillane is proposed for the sesquiterpene skeleton in asperaculin A (1).
引用
收藏
页码:1650 / 1652
页数:3
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