HIGH DIETARY FLUORINE INDUCTION OF OXIDATIVE DAMAGE IN THE CECAL TONSIL OF BROILERS

被引：0

作者：

Liu, Juan ^{[1
]}

Cui, Hengmin ^{[1
]}

Peng, Xi ^{[1
]}

Fang, Jing ^{[1
]}

Zuo, Zhicai ^{[1
]}

Wang, Hesong ^{[1
]}

Wu, Bangyuan ^{[1
]}

Deng, Yuanxin ^{[1
]}

Wang, Kangping ^{[1
]}

机构：

[1] Sichuan Agr Univ, Coll Vet Med, Yaan 625014, Sichuan, Peoples R China

来源：

FLUORIDE | 2012年 / 45卷 / 01期

关键词：

Antioxidation; Broilers; Cecal Tonsil; Fluorine; Lipid peroxidation; INDUCED HEPATOTOXICITY; SODIUM-FLUORIDE; STRESS; SPLEEN;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

As part of our study on the effects of high F on lymphoid organs and tissues of broilers, the oxidative damage to their cecal tonsil induced by dietary high F was observed while feeding them a control diet containing 22.6 mg F/kg and three high F diets containing 400, 800, and 1200 mg F/kg for high F groups I, II, and III throughout a 42-day experimental period. The results showed that malondialdehyde (MDA) content was significantly higher (p<0.01) in high F groups ll and III than in the control group. In contrast, the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px), glutathione (GSH) contents, and ability to inhibit hydroxyl radical were significantly decreased (p<0.01) in high F groups II and III in comparison with those in the control group. In conclusion, dietary F, in the range of 800-1200 mg/kg, could induce oxidative damage and impair the antioxidation and immune function of the cecal tonsil in broilers.

引用

页码：47 / 52

页数：6

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