CENTRAL SEROUS CHORIORETINOPATHY High-Resolution Imaging of Asymptomatic Fellow Eyes Using Adaptive Optics Scanning Laser Ophthalmoscopy

被引:7
|
作者
Gerardy, Melvin [1 ]
Yesilirmak, Nilufer [1 ]
Legras, Richard [2 ]
Behar-Cohen, Francine [1 ,3 ]
Bousquet, Elodie [1 ,3 ]
机构
[1] Univ Paris, Dept Ophthalmol, Hop Cochin, AP HP,OphtalmoPole, 8 Rue Mechain, F-75014 Paris, France
[2] Univ Paris Saclay, Lab Lumiere Mat & Interfaces, CNRS, Cent Supelec,ENS Paris Saclay, Orsay, France
[3] Univ Paris, Ctr Rech Cordeliers, Physiopathol Ccular Dis Therapeut Innovat, INSERM U1138, Paris, France
来源
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2022年 / 42卷 / 02期
关键词
central serous chorioretinopathy; pachychoroid; adaptive optics; optical coherence tomography; CONE DENSITY;
D O I
10.1097/IAE.0000000000003311
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To investigate cone density in the asymptomatic fellow eye of patients with unilateral central serous chorioretinopathy (CSCR). Methods: Seventeen asymptomatic fellow eyes of patients with unilateral CSCR and 17 eyes of aged-matched and gender-matched healthy controls underwent adaptive optics ophthalmoscopy. Cone density and spacing were assessed at the fovea. Clinical and multimodal imaging findings were also recorded. Results: In the CSCR group, the patient mean age was 48.9 +/- 9.8 years. The mean (+/- SD) subfoveal choroidal thickness was 417.8 +/- 125.2 mu m. The foveal external limiting membrane and ellipsoid zone were intact in all patients. Adaptive optics fundus imaging showed a significant decrease in cone density at 2 degrees of eccentricity nasal and temporal to the fovea in asymptomatic fellow eyes of patients with unilateral CSCR compared with controls (P = 0.001 and P = 0.027, respectively). No statistically significant difference in cone density was found at 4 degrees of eccentricity nasal and temporal to the fovea between both groups. Conclusion: Asymptomatic fellow eyes of patients with unilateral CSCR showed a reduced density of foveal cones in the absence of a decreased visual acuity and photoreceptor line disruption on optical coherence tomography. These results suggest that the photoreceptors could be damaged independently of the occurrence of a serous retinal detachment.
引用
收藏
页码:375 / 380
页数:6
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